GRM2 抗体 (AA 681-715)
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Quick Overview for GRM2 抗体 (AA 681-715) (ABIN5708176)
抗原
See all GRM2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 681-715
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原理
- mGluR2 Antibody / Metabotropic Glutamate Receptor 2 / GRM2 (C-Terminal Region)
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交叉反应 (详细)
- Expected species reactivity: Rat
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纯化方法
- Antigen affinity
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免疫原
- A portion of amino acids 681-715 from human GRM2 was used as the immunogen for the mGluR2 antibody.
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亚型
- Ig Fraction
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应用备注
- The stated application concentrations are suggested starting points. Titration of the mGluR2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the mGluR2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- GRM2 (Glutamate Receptor, Metabotropic 2 (GRM2))
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别名
- mGluR2
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背景
- G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. May mediate suppression of neurotransmission or may be involved in synaptogenesis or synaptic stabilization.
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UniProt
- Q14416
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途径
- cAMP Metabolic Process, Dicarboxylic Acid Transport
抗原
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