MMP3 抗体 (AA 317-327)
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北京 101111
Quick Overview for MMP3 抗体 (AA 317-327) (ABIN5708004)
抗原
See all MMP3 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 317-327
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纯化方法
- Purified
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纯度
- Protein A affinity chromatography
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免疫原
- Amino acids 317-327 were used as the immunogen for the recombinant MMP3 antibody.
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亚型
- IgG kappa
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anti-Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3) (AA 248-477) antibody
MMP3 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3) (AA 363-477) antibodyMMP3 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal A3 unconjugated
anti-Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3) (AA 278-450) antibodyMMP3 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3) (AA 1-477) antibodyMMP3 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3) antibodyMMP3 适用: 人 WB, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3) (AA 401-477) antibodyMMP3 适用: 人, 大鼠, 小鼠, 兔 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3) (AA 100-477) antibodyMMP3 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3) (C-Term) antibodyMMP3 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3) (AA 22-131) antibodyMMP3 适用: 人 ELISA, IP 宿主: 小鼠 Monoclonal 4C11 unconjugated
anti-Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3) antibodyMMP3 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 4F10 unconjugated
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应用备注
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Optimal dilution of the recombinant MMP3 antibody should be determined by the researcher.
1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. Immunohistochemistry (FFPE): 0.5-0.1 μg/mL for 30 min at RT,Prediluted IHC only format: incubate for 30 min at RT (1) -
限制
- 仅限研究用
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缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the recombinant MMP3 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- MMP3 (Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3))
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别名
- MMP3 / Matrix Metalloproteinase 3
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背景
- The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP3, MMP10 and MMP11 (also designated stromelysin-1, 2 and 3, respectively) activate procollagenase. MMP3 activation of procollagenase can occur via two pathways. Direct activation by MMP3 is slow and activation by MMP3 in conjunction with tissue or plasma proteinases is rapid. MMP10 is expressed in small intestine, and at lower levels in lung and heart. MMP11 is specifically expressed in stromal cells of breast carcinomas and contributes to epithelial cell malignancies.
抗原
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