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MYOD1 抗体

MYOD1 适用: 人 IHC (p) 宿主: 兔 Monoclonal MYOD1-2075R unconjugated
产品编号 ABIN5708000
发货至: 中国
  • 抗原 See all MYOD1 抗体
    MYOD1 (Myogenic Differentiation 1 (MYOD1))
    适用
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    宿主
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    克隆类型
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    单克隆
    标记
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    This MYOD1 antibody is un-conjugated
    应用范围
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    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    Purified
    纯度
    Protein A affinity chromatography
    免疫原
    Recombinant human protein was used as the immunogen for this recombinant MyoD antibody.
    克隆位点
    MYOD1-2075R
    亚型
    IgG kappa
    Top Product
    Discover our top product MYOD1 Primary Antibody
  • 应用备注
    The optimal dilution of the recombinant MyoD antibody for each application should be determined by the researcher.

    1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 min at RT,Prediluted IHC only format: incubate for 30 min at RT (1)
    限制
    仅限研究用
  • 缓冲液
    1 mg/mL in 1X PBS, BSA free, sodium azide free
    储存液
    Azide free
    储存条件
    4 °C,-20 °C
    储存方法
    Store the recombinant MyoD antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
  • 抗原
    MYOD1 (Myogenic Differentiation 1 (MYOD1))
    别名
    MyoD1 (MYOD1 产品)
    别名
    MYF3 antibody, MYOD antibody, PUM antibody, bHLHc1 antibody, MyoD antibody, XMyoD antibody, XtmyoD antibody, mf25 antibody, myf3 antibody, pum antibody, MUF3 antibody, AI503393 antibody, Myod-1 antibody, etID309723.25 antibody, myod antibody, wu:fb57a01 antibody, zgc:136744 antibody, MYOD1 antibody, myod1 antibody, mf1 antibody, myod1-a antibody, myod1-b antibody, myogenic differentiation 1 antibody, MYOD protein antibody, myogenic factor MyoD1 antibody, myogenic differentiation 1 S homeolog antibody, myogenic differentiation 1 L homeolog antibody, MYOD1 antibody, myod1 antibody, Myod1 antibody, myod antibody, myod1.S antibody, myod1.L antibody
    背景
    MyoD, or MYOD1, is one of the earliest markers of myogenic commitment. MyoD is expressed at extremely low and essentially undetectable levels in quiescent satellite cells, but expression of MyoD is activated in response to exercise or muscle tissue damage. The effect of MyoD on satellite cells is dose-dependent, high MyoD expression represses cell renewal, promotes terminal differentiation and can induce apoptosis. Although MyoD marks myoblast commitment, muscle development is not dramatically ablated in mouse mutants lacking the MyoD gene. This is likely due to functional redundancy from Myf5 and/or Mrf4. Nevertheless, the combination of MyoD and Myf5 is vital to the success of myogenesis. [Wiki]
    途径
    Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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