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CD79a 抗体 (AA 202-216)

This anti-CD79a antibody is a 兔 单克隆 antibody detecting CD79a in IHC (p). Suitable for 人.
产品编号 ABIN5707841
发货至: 中国

Quick Overview for CD79a 抗体 (AA 202-216) (ABIN5707841)

抗原

See all CD79a (CD79A) 抗体
CD79a (CD79A) (B-cell antigen receptor complex-associated protein alpha chain (CD79A))

适用

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宿主

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克隆类型

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单克隆

标记

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This CD79a antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

CDLA79a-3R
  • 抗原表位

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    AA 202-216

    纯化方法

    Purified

    纯度

    Protein A affinity chromatography

    免疫原

    Amino acids 202-216 (GTYQDVGSLNIADVQ) were used as the immunogen for the recombinant CD79a antibody.

    亚型

    IgG kappa
  • 应用备注

    The stated application concentrations are suggested starting points. Titration of the CD79a antibody may be required due to differences in protocols and secondary/substrate sensitivity.

    1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. Immunohistochemistry (FFPE): 0.25-0.5 μg/mL for 30 min at RT,Prediluted IHC only format: incubate for 30 min at RT (1)

    限制

    仅限研究用
  • 缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    Store the recombinant CD79a antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
  • 抗原

    CD79a (CD79A) (B-cell antigen receptor complex-associated protein alpha chain (CD79A))

    别名

    CD79a

    背景

    The CD79a protein together with the related CD79b protein, forms a dimer associated with membrane-bound immunoglobulin in B-cells, thus forming the B-cell antigen receptor (BCR). CD79a plays multiple and diverse roles in B cell development and function. The CD79a/b heterodimer associates non-covalently with the immunoglobulin heavy chain through its transmembrane region, thus forming the BCR along with the immunoglobulin light chain and the pre-BCR when associated with the surrogate light chain in developing B cells. Association of the CD79a/b heterodimer with the immunoglobulin heavy chain is required for surface expression of the BCR and BCR induced calcium flux and protein tyrosine phosphorylation. [Wiki]

    途径

    BCR Signaling
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