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Recombinant Thyroglobulin 抗体

The 兔 单克隆 anti-Thyroglobulin antibody (Clone TGB-1970R) (ABIN5707705) specifically detects Thyroglobulin in IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN5707705
发货至: 中国
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Quick Overview for Recombinant Thyroglobulin 抗体 (ABIN5707705)

抗原

See all Thyroglobulin (TG) 抗体
Thyroglobulin (TG)

抗体类型

Recombinant Antibody

适用

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宿主

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克隆类型

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单克隆

标记

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This Thyroglobulin antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

质量等级

Carrier-free

克隆位点

TGB-1970R
  • 原理

    Recombinant TG Antibody / Rabbit Monoclonal (azide and preservative free)

    交叉反应 (详细)

    Not suitable for mouse

    纯化方法

    Protein A affinity chromatography

    免疫原

    Human thyroid follicular cells were used as the immunogen for the recombinant TG antibody.

    亚型

    IgG, kappa
  • 应用备注

    The stated application concentrations are suggested starting points. Titration of the recombinant TG antibody may be required due to differences in protocols and secondary/substrate sensitivity.

    1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    Store the recombinant TG antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
  • 抗原

    Thyroglobulin (TG)

    别名

    TG

    背景

    Thyroglobulin (Tg) is a 660 kDa, dimeric protein produced by the follicular cells of the thyroid and used entirely within the thyroid gland. Thyroglobulin protein accounts for approximately half of the protein content of the thyroid gland. Human TG (HTG) is a homodimer of subunits each containing 2768 amino acids as synthesized (a short signal peptide may be removed from the N-terminus in the mature protein).

    The protein is a precursor of the thyroid hormones, these are produced when thyroglobulin's tyrosine residues are combined with iodine and the protein is subsequently cleaved. Each thyroglobulin molecule contains approximately 100-120 tyrosine residues, but only a small number (20) of these are subject to iodination by thyroperoxidase in the follicular colloid. Therefore, each Tg molecule forms only approximately 10 thyroid hormone molecules. [Wiki]

    UniProt

    P01266

    途径

    Thyroid Hormone Synthesis
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