MUC16 抗体
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北京 101111
Quick Overview for MUC16 抗体 (ABIN5707666)
抗原
See all MUC16 (CA125) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
- Purified
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纯度
- Protein A affinity chromatography
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免疫原
- A recombinant partial protein was used as the immunogen for the recombinant MUC16 antibody.
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亚型
- IgG kappa
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anti-Mucin 16, Cell Surface Associated (CA125) (AA 1-200) antibody
CA125 适用: 人 IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 4C8C8 unconjugated
anti-Mucin 16, Cell Surface Associated (CA125) (AA 13977-14117) antibodyCA125 适用: 人 IHC, WB, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Mucin 16, Cell Surface Associated (CA125) antibodyCA125 适用: 人 IHC, StM 宿主: 兔 Monoclonal OCA125-2349R unconjugated Recombinant Antibody
anti-Mucin 16, Cell Surface Associated (CA125) (AA 2-258) antibodyCA125 适用: 小鼠 IHC, WB, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Mucin 16, Cell Surface Associated (CA125) (AA 14067-14328) antibodyCA125 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Mucin 16, Cell Surface Associated (CA125) antibodyCA125 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Mucin 16, Cell Surface Associated (CA125) antibodyCA125 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal MUC16-1860 unconjugated
anti-Mucin 16, Cell Surface Associated (CA125) (AA 10329-10628) antibodyCA125 适用: 人 IHC, WB, IHC (p) 宿主: 小鼠 Monoclonal 3B6 unconjugated
anti-Mucin 16, Cell Surface Associated (CA125) (AA 10329-10628) antibodyCA125 适用: 人 IHC, WB, IHC (p) 宿主: 小鼠 Monoclonal 2C4 unconjugated
anti-Mucin 16, Cell Surface Associated (CA125) antibodyCA125 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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Optimal dilution of the recombinant MUC16 antibody should be determined by the researcher.
1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. Immunohistochemistry (FFPE): 1-2 μg/mL for 30 min at RT,Prediluted IHC only format: incubate for 30 min at RT (1) -
限制
- 仅限研究用
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the recombinant MUC16 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- MUC16 (CA125) (Mucin 16, Cell Surface Associated (CA125))
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别名
- MUC16 / CA125
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背景
- The mucins are a family of highly glycosylated, secreted proteins with a basic structure consisting of a variable number of tandem repeats (VNTRs). Membrane-associated and secretory mucins are high molecular weight glycoproteins of the glycocalyx (polysaccharide biofilm) that protects mucosal epithelium from particulate matter and microorganisms. Epithelial mucins are large, secreted and cell surface glycoproteins crucial for adhesion modulation, signaling and epithelial cell protection. The number of repeats is highly polymorphic and varies among different alleles. The Mucin family consists of Mucins 1-4, Mucin 5 (AC and B), 6-8, 11-13 and 15-17. The Mucin 16 protein (also commonly referred to as CA125), encoded for by the gene MUC16, is a very high molecular weight tumor antigen consisting of three domains: a carboxy terminal domain, an extracellular domain and an amino terminal domain. Mucin 16, an ovarian cancer-associated antigen, is used as a marker to monitor the progress of epithelial ovarian cancer. It is a hydrophilic membrane-associated protein that may be involved in vitamin A functions.
抗原
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