TIMP1 抗体
Quick Overview for TIMP1 抗体 (ABIN5707658)
抗原
See all TIMP1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
- Purified
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纯度
- Protein A affinity chromatography
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免疫原
- Recombinant human protein was used as the immunogen for this recombinant TIMP1 antibody.
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亚型
- IgG kappa
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anti-TIMP Metallopeptidase Inhibitor 1 (TIMP1) (AA 103-207) antibody
TIMP1 适用: 人, 大鼠, 小鼠, 兔 WB, ELISA, IF (p), IHC (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-TIMP Metallopeptidase Inhibitor 1 (TIMP1) (AA 157-188), (C-Term) antibodyTIMP1 适用: 人 WB, FACS, IHC (p), IF 宿主: 兔 Polyclonal RB14602 unconjugated
anti-TIMP Metallopeptidase Inhibitor 1 (TIMP1) (AA 41-70), (N-Term) antibodyTIMP1 适用: 人 WB, FACS, IHC (p), IF 宿主: 兔 Polyclonal RB15494 unconjugated
anti-TIMP Metallopeptidase Inhibitor 1 (TIMP1) (AA 25-207) antibodyTIMP1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-TIMP Metallopeptidase Inhibitor 1 (TIMP1) (AA 24-207) antibodyTIMP1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-TIMP Metallopeptidase Inhibitor 1 (TIMP1) antibodyTIMP1 适用: 人 WB, IHC, ELISA 宿主: 小鼠 Monoclonal 8B4E9 unconjugated
anti-TIMP Metallopeptidase Inhibitor 1 (TIMP1) (AA 1-169) antibodyTIMP1 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 4D12 unconjugated
anti-TIMP Metallopeptidase Inhibitor 1 (TIMP1) (AA 24-207) antibodyTIMP1 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-TIMP Metallopeptidase Inhibitor 1 (TIMP1) (AA 131-207) antibodyTIMP1 适用: 人, 大鼠, 小鼠 WB, ELISA, IF (p), IHC (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-TIMP Metallopeptidase Inhibitor 1 (TIMP1) (AA 24-217) antibodyTIMP1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Optimal dilution of the recombinant TIMP1 antibody should be determined by the researcher.
1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. Immunohistochemistry (FFPE): 1-2 μg/mL for 30 min at RT,Prediluted IHC only format : incubate for 30 min at RT (1) -
限制
- 仅限研究用
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缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the recombinant TIMP1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- TIMP1 (TIMP Metallopeptidase Inhibitor 1 (TIMP1))
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别名
- TIMP1
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背景
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TIMP1 is an inhibitory molecule that regulates matrix metalloproteinases (MMPs), and disintegrin-metalloproteinases (ADAMs and ADAMTSs). In regulating MMPs, TIMP1 plays a crucial role in extracellular matrix (ECM) composition, wound healing, and pregnancy.
The dysregulated activity of TIMP1 has been implicated in cancer. In pregnancy, TIMP1 plays a regulatory role in the process of implantation, particularly the cytotrophoblast invasion of the uterine endometrium. Additionally, it plays a role in regulating the transcriptional profile of fetal and placental tissues associated with the early stages of pregnancy. Studies attribute this role to a mechanism involving the chromatin structure at the TIMP1 promoter region, implicating new pharmaceutical possibilities for the therapeutic regulation of TIMP1. Accordingly, TIMP1 can be manipulated in vitro using techniques, like the TIMP1 knock-out. [Wiki]
抗原
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