Hemoglobin Subunit beta 抗体 (N-Term)
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- 抗原 See all Hemoglobin Subunit beta (HBB) 抗体
- Hemoglobin Subunit beta (HBB) (Hemoglobin beta (HBB))
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抗原表位
- N-Term
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Hemoglobin Subunit beta antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- Supplier Product No.
- 200-301-gs4
- Supplier
- Rockland
- 原理
- Hemoglobin A (beta chain) Antibody
- 交叉反应 (详细)
- This protein A purified mouse monoclonal antibody reacts specifically with human HbA beta chain isoform.
- 产品特性
- Synonyms: mouse anti-HbA antibody, mouse anti-hemoglobin antibody, Hemoglobin beta subunit, Hemoglobin subunit beta, Hemoglobin beta chain, HBB, HBA, Hbβ Antibody, LVV-hemorphin-7, Spinorphin, Sickle Cell Disease (SCD)
- 纯化方法
- Anti-Hemoglobin beta β is purified from tissue culture supernatant by protein A purification.
- 过滤
- Sterile filtered
- 免疫原
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Immunogen: Anti-Hemoglobin A (beta chain) Monoclonal Antibody was produced in mice by repeated immunizations with synthetic peptide corresponding to amino acid residues near the N-terminus of Hb beta-subunit conjugated to KLH.
Immunogen Type: Conjugated Peptide
- 克隆位点
- 14G2-G11-F11
- 亚型
- IgG2a lambda
- Top Product
- Discover our top product HBB Primary Antibody
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- 应用备注
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Application Note: Anti-Hemoglobin A (beta chain) (MOUSE) antibody has been tested by ELISA and western blot. This antibody is designed for use in lateral flow. Specific conditions of reactivity should be optimized by the end user. Expect a band of approximately 16 kDa.
Western Blot Dilution: 1 μg/mL
ELISA Dilution: 1:20,000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1.00 mg/mL
- 缓冲液
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: None
Preservative: 0.01 % (w/v) Sodium Azide - 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store vial at -20° C prior to opening. This product is stable at 4° C as an undiluted liquid. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use.
- 有效期
- 12 months
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- 抗原
- Hemoglobin Subunit beta (HBB) (Hemoglobin beta (HBB))
- 别名
- HBB (HBB 产品)
- 物质类
- Viral Protein
- 背景
- Background: HbA antibodies detect the hemoglobin beta subunit wild type variant A isoform. Functional adult hemoglobin (Hb) is a hetero tetramer composed of 2 alpha and 2 beta subunits (α2β2). Common isoform variants of hemoglobin include HbA, HbS, HbC, HbF, and HbA-2. Sickle cell disease (SCD), thalassemias and hemoglobinopathies occur when aberrant forms of hemoglobin are expressed in children and adults. Globin gene mutations affect the structure and expression levels of Hb. Sickle cell disease and the more benign sickle cell trait are observed in more than 100 million people globally. Perhaps the most significant mutation is the E6V in the beta subunit and the cause of SCD, but other relevant isoforms of Hb are observed. HbA antibody cross reacts with HbA-2 but does not react other forms Hb. This antibody is ideal for investigators involved in Cardiovascular and developmental biology research.
- 基因ID
- 3043
- NCBI登录号
- NP_000509
- UniProt
- P68871
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