HBd 抗体 (N-Term)
Quick Overview for HBd 抗体 (N-Term) (ABIN5706735)
抗原
See all HBd 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- N-Term
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Supplier Product No.
- 200-301-gs8
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Supplier
- Rockland
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原理
- Hemoglobin beta A-2 Antibody
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交叉反应 （详细）
- This protein A purified mouse monoclonal antibody reacts specifically with human HbA-2 delta isoform.
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产品特性
- Synonyms: mouse anti-HbA-2 antibody, mouse anti-hemoglobin antibody, Hemoglobin Subunit Delta, Hemoglobin Delta Chain 4, Delta-Globin 4, HbD, HbA-2 Antibody, Sickle Cell Disease (SCD)
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纯化方法
- Anti-HbA-2 is purified from tissue culture supernatant by protein A purification.
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过滤
- Sterile filtered
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免疫原
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Immunogen: Anti-Hemoglobin beta A-2 Monoclonal Antibody was produced in mice by repeated immunizations with synthetic peptide corresponding to amino acid residues near the N-terminus of Hb delta-subunit conjugated to KLH.
Immunogen Type: Conjugated Peptide
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亚型
- IgG1 kappa
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anti-Hemoglobin, delta (HBd) (AA 1-143) antibody
HBd 适用: 人 WB, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Hemoglobin, delta (HBd) (AA 2-147) antibodyHBd 适用: 人, 大鼠, 小鼠 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Hemoglobin, delta (HBd) (AA 2-147) antibodyHBd 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Hemoglobin, delta (HBd) (AA 1-147) antibodyHBd 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Application Note: Anti-Hemoglobin beta A-2 (MOUSE) antibody has been tested by ELISA and Western Blotting. This antibody is designed for use in lateral flow. Specific conditions of reactivity should be optimized by the end user. Expect a band of approximately 16 kDa.
Western Blot Dilution: 1 μg/mL
ELISA Dilution: 1:20,000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.00 mg/mL
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缓冲液
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: None
Preservative: 0.01 % (w/v) Sodium Azide -
储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at -20° C prior to opening. This product is stable at 4° C as an undiluted liquid. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use.
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有效期
- 12 months
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- HBd (Hemoglobin, delta (HBd))
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别名
- HBD
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背景
- Background: HbA-2 or hemoglobin delta subunit antibodies detect the delta-specific sequence in the hemoglobin delta-subunit found in HbA-2. Functional hemoglobin (Hb) is a hetero tetramer and the dominant form of Adult Hb is composed of 2 alpha and 2 beta subunits (α2β2). Hemoglobin A-2 (HbA-2) is a normal but minor variant of hemoglobin A that consists of two alpha and two delta chains (α2δ2). Hemoglobin A-2 may be increased in beta thalassemia or in people who are heterozygous for the beta thalassemia gene, and HbA2 is also linked to neurological disorders. HbA-2 form exists in small amounts in all adult humans (1.5-3.1 % of all hemoglobin molecules) and is increased in people with Sickle-cell disease. Its normal biological role is not well understood. HbA-2 antibody does not react other forms of Hb including no cross-reaction to HbA or beta subunit. This antibody is ideal for investigators involved in Cardiovascular and developmental biology research.
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基因ID
- 3045
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NCBI登录号
- NP_000510
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UniProt
- P02042
抗原
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