TSG101 抗体
Quick Overview for TSG101 抗体 (ABIN5706095)
抗原
See all TSG101 抗体适用
宿主
克隆类型
标记
应用范围
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免疫原
- tumor susceptibility gene 101
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亚型
- IgG
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应用备注
- WB:1:200-1:2000,IP:1:200-1:2000,IHC:1:100-1:500,IF:1:10-1:100
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说明
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HeLa cells were subjected to SDS PAGE followed by western blot with FNab09040(TSG101 antibody) at dilution of 1:500
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限制
- 仅限研究用
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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有效期
- 12 months
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- TSG101 (Tumor Susceptibility Gene 101 (TSG101))
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别名
- TSG101
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背景
- Synonyms:ESCRT I complex subunit TSG101, TSG10, TSG101, tumor susceptibility gene 101, VPS23 Background:The protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression.
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分子量
- 46kDa
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基因ID
- 7251
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UniProt
- Q99816
抗原
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