MBNL3 抗体
Quick Overview for MBNL3 抗体 (ABIN5705442)
抗原
See all MBNL3 抗体适用
宿主
克隆类型
标记
应用范围
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免疫原
- muscleblind-like 3 (Drosophila)
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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mouse skeletal muscle tissue were subjected to SDS PAGE followed by western blot with FNab05041( MBNL3 Antibody) at dilution of 1:600
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限制
- 仅限研究用
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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有效期
- 12 months
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- MBNL3 (Muscleblind-Like Splicing Regulator 3 (MBNL3))
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别名
- MBNL3
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背景
- Synonyms:CHCR, MBLX39, MBXL Background:Mediates pre-mRNA alternative splicing regulation. Acts either as activator or repressor of splicing on specific pre-mRNA targets. Inhibits cardiac troponin-T(TNNT2) pre-mRNA exon inclusion but induces insulin receptor(IR) pre-mRNA exon inclusion in muscle. Antagonizes the alternative splicing activity pattern of CELF proteins. May play a role in myotonic dystrophy pathophysiology(DM). Could inhibit terminal muscle differentiation, acting at approximately the time of myogenin induction.
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分子量
- 38 kDa
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基因ID
- 55796
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UniProt
- Q9NUK0
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途径
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
抗原
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