PARD3 抗体
Quick Overview for PARD3 抗体 (ABIN5704096)
抗原
See all PARD3 抗体适用
宿主
克隆类型
标记
应用范围
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免疫原
- par-3 partitioning defective 3 homolog (C. elegans)
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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MCF7 cells were subjected to SDS PAGE followed by western blot with FNab06146(PARD3 antibody) at dilution of 1:300
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限制
- 仅限研究用
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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有效期
- 12 months
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- PARD3 (Par-3 Partitioning Defective 3 Homolog (PARD3))
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别名
- PARD3
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背景
- Synonyms:ASIP, Baz, Bazooka, CTCL tumor antigen se2 5, FLJ21015, PAR 3, PAR3, PAR3 alpha, PAR3A, PAR3alpha, PARD 3, PARD3, PARD3A, SE2 5L16, SE2 5LT1, SE2 5T2 Background:Adapter protein involved in asymmetrical cell division and cell polarization processes. Seems to play a central role in the formation of epithelial tight junctions. Targets the phosphatase PTEN to cell junctions. Involved in Schwann cell peripheral myelination(By similarity). Association with PARD6B may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins. Required for establishment of neuronal polarity and normal axon formation in cultured hippocampal neurons.PARD3 has three splice isoforms at 100 kDa, 150 kDa, and 180 kDa. This polyclonal antibody raised against C-terminal 281 amino acids of human PARD3 recognizes these three isoforms.
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基因ID
- 56288
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UniProt
- Q8TEW0
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途径
- Cell-Cell Junction Organization
抗原
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