PSMC2 抗体
Quick Overview for PSMC2 抗体 (ABIN5703325)
抗原
See all PSMC2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
原理
- PSMC2 antibody
-
免疫原
- proteasome (prosome, macropain) 26S subunit, ATPase, 2
-
亚型
- IgG
-
-
anti-Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 2 (PSMC2) (AA 1-433) antibody
PSMC2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 2 (PSMC2) (AA 1-160) antibodyPSMC2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 2 (PSMC2) (AA 1-433) antibodyPSMC2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4C10-2C8 unconjugated
anti-Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 2 (PSMC2) antibodyPSMC2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 2 (PSMC2) antibodyPSMC2 适用: 人 WB 宿主: 小鼠 Monoclonal 1851CT193-4-40 unconjugated
anti-Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 2 (PSMC2) (Internal Region) antibodyPSMC2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 2 (PSMC2) antibodyPSMC2 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 2 (PSMC2) antibodyPSMC2 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 2 (PSMC2) (N-Term) antibodyPSMC2 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 兔, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 2 (PSMC2) antibodyPSMC2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal unconjugated
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
说明
-
human adrenal gland tissue were subjected to SDS PAGE followed by western blot with FNab06878(PSMC2 antibody) at dilution of 1:500
-
限制
- 仅限研究用
-
-
-
缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze / thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- -20°C for 12 months
-
有效期
- 12 months
-
-
- PSMC2 (Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 2 (PSMC2))
-
别名
- PSMC2
-
背景
-
Synonyms: 26S proteasome regulatory subunit 7|26S proteasome AAA-ATPase subunit RPT1|Proteasome 26S subunit ATPase 2|PSMC2|MSS1
Background: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. This subunit has been shown to interact with several of the basal transcription factors so, in addition to participation in proteasome functions, this subunit may participate in the regulation of transcription. This subunit may also compete with PSMC3 for binding to the HIV tat protein to regulate the interaction between the viral protein and the transcription complex. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
-
基因ID
- 5701
-
UniProt
- P35998
-
途径
- Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway
抗原
-
