EIF4G1 抗体
Quick Overview for EIF4G1 抗体 (ABIN5702756)
抗原
See all EIF4G1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- EIF4G1 antibody
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免疫原
- eukaryotic translation initiation factor 4 gamma, 1
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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HeLa cells were subjected to SDS PAGE followed by western blot with FNab02724(EIF4G1 antibody) at dilution of 1:1000
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限制
- 仅限研究用
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- EIF4G1 (Eukaryotic Translation Initiation Factor 4 Gamma, 1 (EIF4G1))
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别名
- EIF4G1
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背景
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Synonyms: Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1, eIF-4G 1, eIF-4G1)|p220|EIF4G1|EIF4F|EIF4G|EIF4GI
Background: The protein encoded by this gene is a component of the multi-subunit protein complex EIF4F. This complex facilitates the recruitment of mRNA to the ribosome, which is a rate-limiting step during the initiation phase of protein synthesis. The recognition of the mRNA cap and the ATP-dependent unwinding of 5'-terminal secondary structure is catalyzed by factors in this complex. The subunit encoded by this gene is a large scaffolding protein that contains binding sites for other members of the EIF4F complex. A domain at its N-terminus can also interact with the poly(A)-binding protein, which may mediate the circularization of mRNA during translation. Alternative splicing results in multiple transcript variants, some of which are derived from alternative promoter usage.
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分子量
- 250 kDa
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基因ID
- 1981
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UniProt
- Q04637
抗原
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