STING1 (AA 170-379) 抗体
Quick Overview for STING1 (AA 170-379) 抗体 (ABIN5701799)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 170-379
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原理
- STING1 antibody
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免疫原
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Immunogen sequence: 170-379aa
Immunogen: transmembrane protein 173
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亚型
- IgG
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anti-STING1 (AA 190-290) antibody
适用: 人 IHC 宿主: 小鼠 Monoclonal MSVA-515M unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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mouse thymus tissue were subjected to SDS PAGE followed by western blot with FNab08759(TMEM173 antibody) at dilution of 1:500
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限制
- 仅限研究用
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- STING1
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背景
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Synonyms: Stimulator of interferon genes protein (hSTING)|Endoplasmic reticulum interferon stimulator (ERIS)|Mediator of IRF3 activation (hMITA)|Transmembrane protein 173|STING1|ERIS|MITA|STING|TMEM173
Background: This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants.
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基因ID
- 340061
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UniProt
- Q86WV6
抗原
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