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Acetyl-CoA Carboxylase alpha 抗体 (AA 2223-2346)

The 兔 多克隆 anti-Acetyl-CoA Carboxylase alpha antibody is suitable to detect Acetyl-CoA Carboxylase alpha in samples from 人, 小鼠 和 大鼠. It has been validated for WB, IHC, ELISA, IP 和 IF.
产品编号 ABIN5701229
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Acetyl-CoA Carboxylase alpha 抗体 (AA 2223-2346) (ABIN5701229)

抗原

See all Acetyl-CoA Carboxylase alpha (ACACA) 抗体
Acetyl-CoA Carboxylase alpha (ACACA)

适用

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人, 小鼠, 大鼠

宿主

  • 100
  • 5
  • 1

克隆类型

  • 92
  • 14
多克隆

标记

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This Acetyl-CoA Carboxylase alpha antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP), Immunofluorescence (IF)
  • 抗原表位

    • 29
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    AA 2223-2346

    原理

    ACACA antibody

    免疫原

    Immunogen sequence: 2223-2346aa

    Immunogen: acetyl-Coenzyme A carboxylase alpha

    亚型

    IgG
  • 应用备注

    WB :1:200-1:2000,IHC:1:20-1:200,IF:1:20-1:200,IP:1:200-1:2000

    说明

    HeLa cells were subjected to SDS PAGE followed by western blot with FNab00077(ACACA antibody) at dilution of 1:500

    限制

    仅限研究用
  • 缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months

    有效期

    12 months
  • 抗原

    Acetyl-CoA Carboxylase alpha (ACACA)

    别名

    ACACA

    背景

    Synonyms: Acetyl-CoA carboxylase 1 (ACC1)|Acetyl-Coenzyme A carboxylase alpha (ACC-alpha)|ACACA|ACAC|ACC1|ACCA

    Background: ACACA(Acetyl-CoA carboxylase 1, ACC), also named as ACAC, ACC1 and ACCA, belongs to the biotin containing enzyme family. It catalyzes the synthesis of malonyl-CoA, which is an intermediate substrate playing a pivotal role in the regulation of fatty acid metabolism and energy production. ACACA is involved in the biosynthesis of fatty acids, and malonyl-CoA produced is used as a building block to extend the chain length of fatty acids by fatty acid synthase(FAS)(PMID:19900410). It has 4 isoforms produced by alternative promoter usage with the molecular weight between 260 kDa and 270 kDa.

    分子量

    270kDa

    UniProt

    Q13085

    途径

    AMPK Signaling, Ribonucleoside Biosynthetic Process, Warburg Effect
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