LITAF 抗体
Quick Overview for LITAF 抗体 (ABIN5701043)
抗原
See all LITAF 抗体适用
宿主
克隆类型
标记
应用范围
-
-
免疫原
- lipopolysaccharide-induced TNF factor
-
亚型
- IgG
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
说明
-
HeLa cells were subjected to SDS PAGE followed by western blot with FNab04798(LITAF antibody) at dilution of 1:500
-
限制
- 仅限研究用
-
-
-
缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze / thaw cycles.
-
储存条件
- -20 °C
-
有效期
- 12 months
-
-
- LITAF (Lipopolysaccharide-Induced Tumor Necrosis Factor-alpha Factor (LITAF))
-
别名
- LITAF
-
背景
- Synonyms:PIG7, SIMPLE Background:Lipopolysaccharide is a potent stimulator of monocytes and macrophages, causing secretion of tumor necrosis factor-alpha (TNF-alpha) and other inflammatory mediators. This gene encodes lipopolysaccharide-induced TNF-alpha factor, which is a DNA-binding protein and can mediate the TNF-alpha expression by direct binding to the promoter region of the TNF-alpha gene. The transcription of this gene is induced by tumor suppressor p53 and has been implicated in the p53-induced apoptotic pathway. Mutations in this gene cause Charcot-Marie-Tooth disease type 1C (CMT1C) and may be involved in the carcinogenesis of extramammary Paget's disease (EMPD). Multiple alternatively spliced transcript variants have been found for this gene.
-
分子量
- 24 kDa
-
基因ID
- 9516
-
UniProt
- Q99732
-
途径
- Cellular Response to Molecule of Bacterial Origin
抗原
-