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COMT 抗体

This anti-COMT antibody is a 兔 多克隆 antibody detecting COMT in WB, IHC, ELISA, IP, IF 和 FACS. Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN5700530
发货至: 中国

Quick Overview for COMT 抗体 (ABIN5700530)

抗原

See all COMT 抗体
COMT (Catechol-O-Methyltransferase (COMT))

适用

  • 60
  • 48
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  • 5
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  • 2
  • 1
  • 1
人, 大鼠, 小鼠

宿主

  • 70
  • 22
  • 3
  • 1

克隆类型

  • 66
  • 30
多克隆

标记

  • 64
  • 5
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This COMT antibody is un-conjugated

应用范围

  • 61
  • 41
  • 29
  • 25
  • 23
  • 13
  • 13
  • 8
  • 8
  • 3
  • 3
  • 3
  • 2
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP), Immunofluorescence (IF), Flow Cytometry (FACS)
  • 免疫原

    catechol-O-methyltransferase

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    mouse liver tissue were subjected to SDS PAGE followed by western blot with FNab01856( COMT Antibody) at dilution of 1:600

    限制

    仅限研究用
  • 缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    -20 °C

    有效期

    12 months
  • 抗原

    COMT (Catechol-O-Methyltransferase (COMT))

    别名

    COMT

    背景

    Synonyms: Background:Catechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. This O-methylation results in one of the major degradative pathways of the catecholamine transmitters. In addition to its role in the metabolism of endogenous substances, COMT is important in the metabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson disease. COMT is found in two forms in tissues, a soluble form (S-COMT) and a membrane-bound form (MB-COMT). The differences between S-COMT and MB-COMT reside within the N-termini. Several transcript variants are formed through the use of alternative translation initiation sites and promoters.

    分子量

    30 kDa

    基因ID

    1312

    UniProt

    P21964

    途径

    Steroid Hormone Biosynthesis, SARS-CoV-2 Protein Interactome
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