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BAIAP2 抗体

This anti-BAIAP2 antibody is a 兔 多克隆 antibody detecting BAIAP2 in WB, ELISA, IHC 和 IP. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN5700348
发货至: 中国

Quick Overview for BAIAP2 抗体 (ABIN5700348)

抗原

See all BAIAP2 抗体
BAIAP2 (BAI1-Associated Protein 2 (BAIAP2))

适用

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人, 小鼠, 大鼠

宿主

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  • 1

克隆类型

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多克隆

标记

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This BAIAP2 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)
  • 原理

    BAIAP2 antibody

    免疫原

    BAI1-associated protein 2

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab00793( BAIAP2 Antibody) at dilution of 1:600

    限制

    仅限研究用
  • 缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months

    有效期

    12 months
  • 抗原

    BAIAP2 (BAI1-Associated Protein 2 (BAIAP2))

    别名

    BAIAP2

    背景

    Synonyms: Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAI-associated protein 2, BAI1-associated protein 2, Protein BAP2)|Fas ligand-associated factor 3 (FLAF3)|Insulin receptor substrate p53/p58 (IRS-58, IRSp53/58)|Insulin receptor substrate protein of 53 kDa (IRSp53, Insulin receptor substrate p53)|BAIAP2

    Background: The protein encoded by this gene has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This adaptor protein links membrane bound G-proteins to cytoplasmic effector proteins. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis. This protein is involved in lamellipodia and filopodia formation in motile cells and may affect neuronal growth-cone guidance. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

    基因ID

    10458

    UniProt

    Q9UQB8
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