SKAP2 抗体
Quick Overview for SKAP2 抗体 (ABIN5699946)
抗原
See all SKAP2 抗体适用
宿主
克隆类型
标记
应用范围
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免疫原
- src kinase associated phosphoprotein 2
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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human liver tissue were subjected to SDS PAGE followed by western blot with FNab07890(SKAP2 antibody) at dilution of 1:1500
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限制
- 仅限研究用
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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有效期
- 12 months
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- SKAP2 (Src Kinase Associated Phosphoprotein 2 (SKAP2))
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别名
- SKAP2
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背景
- Synonyms:PRAP, RA70, SAPS, SCAP2, SKAP55R Background:The protein encoded by this gene shares homology with Src kinase-associated phosphoprotein 1, and is a substrate of Src family kinases. It is an adaptor protein that is thought to play an essential role in the Src signaling pathway, and in regulating proper activation of the immune system. This protein contains an amino terminal coiled-coil domain for self-dimerization, a plecskstrin homology (PH) domain required for interactions with lipids at the membrane, and a Src homology (SH3) domain at the carboxy terminus. Some reports indicate that this protein inhibits actin polymerization through interactions with actin assembly factors, and might negatively regulate the invasiveness of tumors by modulating actin assembly. Alternative splicing results in multiple transcript variants encoding different isoforms.
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基因ID
- 8935
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UniProt
- O75563
抗原
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