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ADAR 抗体

This anti-ADAR antibody is a 兔 多克隆 antibody detecting ADAR in WB, IHC, ELISA, IF 和 IP. Suitable for 人, 小鼠, 大鼠 和 Pig.
产品编号 ABIN5699808
发货至: 中国

Quick Overview for ADAR 抗体 (ABIN5699808)

抗原

See all ADAR 抗体
ADAR (Adenosine Deaminase, RNA-Specific (ADAR))

适用

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人, 小鼠, 大鼠, Pig

宿主

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  • 1

克隆类型

  • 70
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多克隆

标记

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This ADAR antibody is un-conjugated

应用范围

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  • 27
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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP)
  • 原理

    ADAR antibody

    免疫原

    Immunogen sequence: Peptide

    Immunogen: adenosine deaminase, RNA-specific

    亚型

    IgG
  • 应用备注

    WB :1:500-1:5000,IHC:1:20-1:200,IP:1:200-1:2000,IF:1:20-1:200

    说明

    HeLa cells were subjected to SDS PAGE followed by western blot with FNab00150( ADAR1 Antibody) at dilution of 1:1000

    限制

    仅限研究用
  • 缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months

    有效期

    12 months
  • 抗原

    ADAR (Adenosine Deaminase, RNA-Specific (ADAR))

    别名

    ADAR

    背景

    Synonyms: Double-stranded RNA-specific adenosine deaminase (DRADA)|136 kDa double-stranded RNA-binding protein (p136)|Interferon-inducible protein 4 (IFI-4)|K88DSRBP|ADAR|ADAR1|DSRAD|G1P1|IFI4

    Background: ADAR1 is also named as ADAR1, DSRAD, G1P1, IFI4. It convert selected adenosine residues into inosine in substrate RNAs containing a relatively short dsRNA region(PMID:15556947). The human ADAR1 gene specifies two size forms of RNA-specific adenosine deaminase, an interferon(IFN) inducible ?150 kDa protein and a constitutively expressed N-terminally truncated ?110 kDa protein, encoded by transcripts with alternative exon 1 structures that initiate from different promoters(PMID:11111054). It has 5 isoforms produced by alternative promoter usage and alternative splicing. Defects in ADAR are a cause of dyschromatosis symmetrical hereditaria(DSH).ADAR1 can form respective homodimers, and this association is essential for its enzymatic activities(PMID:17428802).

    分子量

    136kDa,observed 110kDa

    UniProt

    P55265

    途径

    Protein targeting to Nucleus
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