HOPX 抗体
Quick Overview for HOPX 抗体 (ABIN5699466)
抗原
See all HOPX 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- HOPX antibody
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免疫原
- HOP homeobox
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- HOPX (HOP Homeobox (HOPX))
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别名
- HOPX
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背景
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Synonyms: Homeodomain-only protein|Lung cancer-associated Y protein|Not expressed in choriocarcinoma protein 1|Odd homeobox protein 1|HOPX|HOD|HOP|LAGY|NECC1|OB1
Background: Atypical homeodomain protein which does not bind DNA and is required to modulate cardiac growth and development. Acts via its interaction with SRF, thereby modulating the expression of SRF-dependent cardiac-specific genes and cardiac development. Prevents SRF-dependent transcription either by inhibiting SRF binding to DNA or by recruiting histone deacetylase(HDAC) proteins that prevent transcription by SRF. Overexpression causes cardiac hypertrophy(By similarity). May act as a tumor suppressor.
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分子量
- 8-12 kDa
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基因ID
- 84525
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UniProt
- Q9BPY8
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途径
- Regulation of Muscle Cell Differentiation
抗原
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