UMPS 抗体
Quick Overview for UMPS 抗体 (ABIN5698683)
抗原
See all UMPS 抗体适用
宿主
克隆类型
标记
应用范围
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免疫原
- uridine monophosphate synthetase
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亚型
- IgG
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应用备注
- WB : 1:500-1:5000,IP:1:200-1:2000,IHC:1:20-1:200
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说明
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HeLa cells were subjected to SDS PAGE followed by western blot with FNab09253(UMPS antibody) at dilution of 1:400
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限制
- 仅限研究用
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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有效期
- 12 months
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- UMPS (Uridine Monophosphate Synthetase (UMPS))
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别名
- UMPS
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背景
- Synonyms:OMPdecase, OPRT, OPRTase, UMPS Background:This gene encodes a uridine 5'-monophosphate synthase. The encoded protein is a bifunctional enzyme that catalyzes the final two steps of the de novo pyrimidine biosynthetic pathway. The first reaction is carried out by the N-terminal enzyme orotate phosphoribosyltransferase which converts orotic acid to orotidine-5'-monophosphate. The terminal reaction is carried out by the C-terminal enzyme OMP decarboxylase which converts orotidine-5'-monophosphate to uridine monophosphate. Defects in this gene are the cause of hereditary orotic aciduria. Alternate splicing results in multiple transcript variants.
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分子量
- 26kDa
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基因ID
- 7372
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UniProt
- P11172
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途径
- Ribonucleoside Biosynthetic Process
抗原
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