RAB7B 抗体
-
- 抗原 See all RAB7B 抗体
- RAB7B (RAB7B, Member RAS Oncogene Family (RAB7B))
- 适用
- 人, 小鼠, 大鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This RAB7B antibody is un-conjugated
-
应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 免疫原
- RAB7B, member RAS oncogene family
- 亚型
- IgG
- Top Product
- Discover our top product RAB7B Primary Antibody
-
-
- 应用备注
- Optimal working dilution should be determined by the investigator.
- 说明
-
human heart tissue were subjected to SDS PAGE followed by western blot with FNab07044(RAB7B antibody) at dilution of 1:200
- 限制
- 仅限研究用
-
- 缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze / thaw cycles.
- 储存条件
- -20 °C
- 有效期
- 12 months
-
- 抗原
- RAB7B (RAB7B, Member RAS Oncogene Family (RAB7B))
- 别名
- RAB7B (RAB7B 产品)
- 别名
- RGD1562617 antibody, RAB7B antibody, RAB7 antibody, Rab7b antibody, Rab7b, member RAS oncogene family antibody, rab7B protein antibody, RAB7B, member RAS oncogene family antibody, RAB7B, member RAS oncogene family S homeolog antibody, Rab7b antibody, rab7B antibody, RAB7B antibody, rab7b.S antibody, rab7b antibody
- 背景
- Synonyms:Ras-related protein Rab-7b, RAB7B Background:Controls vesicular trafficking from endosomes to the trans-Golgi network(TGN). Acts as a negative regulator of TLR9 signaling and can suppress TLR9-triggered TNFA, IL6, and IFNB production in macrophages by promoting TLR9 lysosomal degradation. Also negatively regulates TLR4 signaling in macrophages by promoting lysosomal degradation of TLR4. Promotes megakaryocytic differentiation by increasing NF-kappa-B-dependent IL6 production and subsequently enhancing the association of STAT3 with GATA1. Not involved in the regulation of the EGF-and EGFR degradation pathway.
- 基因ID
- 338382
- UniProt
- Q96AH8
-