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RAB7B 抗体

RAB7B 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5698229
发货至: 中国
  • 抗原 See all RAB7B 抗体
    RAB7B (RAB7B, Member RAS Oncogene Family (RAB7B))
    适用
    人, 小鼠, 大鼠
    宿主
    • 21
    • 6
    克隆类型
    • 23
    • 4
    多克隆
    标记
    • 14
    • 3
    • 3
    • 3
    • 2
    • 2
    This RAB7B antibody is un-conjugated
    应用范围
    • 23
    • 22
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    免疫原
    RAB7B, member RAS oncogene family
    亚型
    IgG
    Top Product
    Discover our top product RAB7B Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    说明

    human heart tissue were subjected to SDS PAGE followed by western blot with FNab07044(RAB7B antibody) at dilution of 1:200

    限制
    仅限研究用
  • 缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze / thaw cycles.
    储存条件
    -20 °C
    有效期
    12 months
  • 抗原
    RAB7B (RAB7B, Member RAS Oncogene Family (RAB7B))
    别名
    RAB7B (RAB7B 产品)
    别名
    RGD1562617 antibody, RAB7B antibody, RAB7 antibody, Rab7b antibody, Rab7b, member RAS oncogene family antibody, rab7B protein antibody, RAB7B, member RAS oncogene family antibody, RAB7B, member RAS oncogene family S homeolog antibody, Rab7b antibody, rab7B antibody, RAB7B antibody, rab7b.S antibody, rab7b antibody
    背景
    Synonyms:Ras-related protein Rab-7b, RAB7B Background:Controls vesicular trafficking from endosomes to the trans-Golgi network(TGN). Acts as a negative regulator of TLR9 signaling and can suppress TLR9-triggered TNFA, IL6, and IFNB production in macrophages by promoting TLR9 lysosomal degradation. Also negatively regulates TLR4 signaling in macrophages by promoting lysosomal degradation of TLR4. Promotes megakaryocytic differentiation by increasing NF-kappa-B-dependent IL6 production and subsequently enhancing the association of STAT3 with GATA1. Not involved in the regulation of the EGF-and EGFR degradation pathway.
    基因ID
    338382
    UniProt
    Q96AH8
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