RAB7B 抗体
Quick Overview for RAB7B 抗体 (ABIN5698229)
抗原
See all RAB7B 抗体适用
宿主
克隆类型
标记
应用范围
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                                            免疫原
- RAB7B, member RAS oncogene family
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                                            亚型
- IgG
 
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                                            应用备注
- Optimal working dilution should be determined by the investigator.
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                                            说明
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                        human heart tissue were subjected to SDS PAGE followed by western blot with FNab07044(RAB7B antibody) at dilution of 1:200 
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                                            限制
- 仅限研究用
 
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                                            缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
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                                            储存液
- Sodium azide
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                                            注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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                                            注意事项
- Avoid repeated freeze / thaw cycles.
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                                            储存条件
- -20 °C
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                                            有效期
- 12 months
 
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    - RAB7B (RAB7B, Member RAS Oncogene Family (RAB7B))
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                                            别名
- RAB7B
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                                            背景
- Synonyms:Ras-related protein Rab-7b, RAB7B Background:Controls vesicular trafficking from endosomes to the trans-Golgi network(TGN). Acts as a negative regulator of TLR9 signaling and can suppress TLR9-triggered TNFA, IL6, and IFNB production in macrophages by promoting TLR9 lysosomal degradation. Also negatively regulates TLR4 signaling in macrophages by promoting lysosomal degradation of TLR4. Promotes megakaryocytic differentiation by increasing NF-kappa-B-dependent IL6 production and subsequently enhancing the association of STAT3 with GATA1. Not involved in the regulation of the EGF-and EGFR degradation pathway.
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                                            基因ID
- 338382
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                                            UniProt
- Q96AH8
 抗原
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