IL-10RA 抗体
Quick Overview for IL-10RA 抗体 (ABIN5698000)
抗原
See all IL-10RA (IL10RA) 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- IL10RA antibody
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免疫原
- interleukin 10 receptor, alpha
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- IL-10RA (IL10RA) (Interleukin 10 Receptor, alpha (IL10RA))
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别名
- IL10RA
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背景
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Synonyms: Interleukin-10 receptor subunit alpha (IL-10 receptor subunit alpha, IL-10R subunit alpha, IL-10RA)|CDw210a|Interleukin-10 receptor subunit 1 (IL-10R subunit 1, IL-10R1)|IL10RA|IL10R
Background: The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene.
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分子量
- 70-72 kDa,90-95 kDa
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基因ID
- 3587
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UniProt
- Q13651
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途径
- Growth Factor Binding
抗原
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