HORMAD1 抗体
Quick Overview for HORMAD1 抗体 (ABIN5697876)
抗原
See all HORMAD1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- HORMAD1 antibody
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免疫原
- HORMA domain containing 1
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- HORMAD1 (HORMA Domain Containing 1 (HORMAD1))
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别名
- HORMAD1
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背景
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Synonyms: HORMA domain-containing protein 1|Cancer/testis antigen 46 (CT46)|Newborn ovary HORMA protein|HORMAD1|NOHMA
Background: Plays a key role in meiotic progression. Regulates 3 different functions during meiosis: ensures that sufficient numbers of processed DNA double-strand breaks(DSBs) are available for successful homology search by increasing the steady-state numbers of single-stranded DSB ends. Promotes synaptonemal-complex formation independently of its role in homology search. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process believed to form the basis of meiotic silencing of unsynapsed chromatin(MSUC) and meiotic prophase quality control in both sexes(By similarity).
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分子量
- 45 kDa
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基因ID
- 84072
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UniProt
- Q86X24
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途径
- M Phase
抗原
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