HDAC4 抗体
Quick Overview for HDAC4 抗体 (ABIN5697851)
抗原
See all HDAC4 抗体适用
宿主
克隆类型
标记
应用范围
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免疫原
- histone deacetylase 4
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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HeLa cells were subjected to SDS PAGE followed by western blot with FNab03800(HDAC4 antibody) at dilution of 1:300
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限制
- 仅限研究用
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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有效期
- 12 months
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- HDAC4 (Histone Deacetylase 4 (HDAC4))
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别名
- HDAC4
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背景
- Synonyms:KIAA0288 Background:Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3.
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分子量
- 119-140 kDa
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基因ID
- 9759
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UniProt
- P56524
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途径
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process
抗原
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