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BCR 抗体

This anti-BCR antibody is a 兔 多克隆 antibody detecting BCR in WB, ELISA, IHC, IF 和 FACS. Suitable for 人 和 猴.
产品编号 ABIN5697146
发货至: 中国

Quick Overview for BCR 抗体 (ABIN5697146)

抗原

See all BCR 抗体
BCR (Breakpoint Cluster Region (BCR))

适用

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人, 猴

宿主

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克隆类型

  • 96
  • 5
多克隆

标记

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  • 1
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This BCR antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)
  • 免疫原

    breakpoint cluster region

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    Y79 cells were subjected to SDS PAGE followed by western blot with FNab00854(BCR antibody) at dilution of 1:1000

    限制

    仅限研究用
  • 缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    -20 °C

    有效期

    12 months
  • 抗原

    BCR (Breakpoint Cluster Region (BCR))

    别名

    BCR

    背景

    Synonyms:BCR1, D22S11 Background:A reciprocal translocation between chromosomes 22 and 9 produces the Philadelphia chromosome, which is often found in patients with chronic myelogenous leukemia. The chromosome 22 breakpoint for this translocation is located within the BCR gene. The translocation produces a fusion protein which is encoded by sequence from both BCR and ABL, the gene at the chromosome 9 breakpoint. Although the BCR-ABL fusion protein has been extensively studied, the function of the normal BCR gene product is not clear. The protein has serine/threonine kinase activity and is a GTPase-activating protein for p21rac. Two transcript variants encoding different isoforms have been found for this gene.

    分子量

    150-160 kDa

    基因ID

    613

    UniProt

    P11274

    途径

    Regulation of Leukocyte Mediated Immunity, Platelet-derived growth Factor Receptor Signaling
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