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BCR 抗体

This 兔 多克隆 anti-BCR antibody specifically detects BCR in WB, IHC, ELISA, IF 和 FACS. The antibody is reactive with 人 和 猴 samples.
产品编号 ABIN5697146
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for BCR 抗体 (ABIN5697146)

抗原

See all BCR 抗体
BCR (Breakpoint Cluster Region (BCR))

适用

  • 110
  • 56
  • 26
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
人, 猴

宿主

  • 103
  • 5
  • 4

克隆类型

  • 96
  • 16
多克隆

标记

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  • 2
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  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
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This BCR antibody is un-conjugated

应用范围

  • 80
  • 38
  • 34
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  • 26
  • 26
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  • 15
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  • 9
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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)
  • 原理

    BCR antibody

    免疫原

    breakpoint cluster region

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    Y79 cells were subjected to SDS PAGE followed by western blot with FNab00854(BCR antibody) at dilution of 1:1000

    限制

    仅限研究用
  • 缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months

    有效期

    12 months
  • 抗原

    BCR (Breakpoint Cluster Region (BCR))

    别名

    BCR

    背景

    Synonyms: Breakpoint cluster region protein|Renal carcinoma antigen NY-REN-26|BCR|BCR1|D22S11

    Background: A reciprocal translocation between chromosomes 22 and 9 produces the Philadelphia chromosome, which is often found in patients with chronic myelogenous leukemia. The chromosome 22 breakpoint for this translocation is located within the BCR gene. The translocation produces a fusion protein which is encoded by sequence from both BCR and ABL, the gene at the chromosome 9 breakpoint. Although the BCR-ABL fusion protein has been extensively studied, the function of the normal BCR gene product is not clear. The protein has serine/threonine kinase activity and is a GTPase-activating protein for p21rac. Two transcript variants encoding different isoforms have been found for this gene.

    分子量

    150-160 kDa

    基因ID

    613

    UniProt

    P11274

    途径

    Regulation of Leukocyte Mediated Immunity, Platelet-derived growth Factor Receptor Signaling
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