TRIM21 抗体 (C-Term)
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Quick Overview for TRIM21 抗体 (C-Term) (ABIN569661)
抗原
See all TRIM21 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- CPLNIGSQGS TDY
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特异性
- Recognizes 52 Kd Ro Protein (TRIM21).
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纯化方法
- Immunoaffinity Chromatography
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免疫原
- Synthetic peptide (CPLNIGSQGSTDY) from C-terminus of Human TRIM21
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Tris saline, pH ~7.3 with 0.02 % Sodium Azide and 0.5 % BSA
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- TRIM21 (Tripartite Motif Containing 21 (TRIM21))
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别名
- SS-A / Ro52 / TRIM21
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背景
- The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein is part of the RoSSA ribonucleoprotein which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. RoSSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus. The function of the RoSSA particle has not been determined. Two alternatively spliced transcript variants for this gene have been described, however, the full length nature of one variant has not been determined.Synonyms: E3 ubiquitin-protein ligase TRIM21, RING finger protein 81, RNF81, Ro(SS-A), SSA1, Sjoegren syndrome type A antigen, TRIM21, Tripartite motif-containing protein 21
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基因ID
- 6737
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NCBI登录号
- NP_003132
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UniProt
- P19474
抗原
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