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SCD 抗体 (C-Term)

The 山羊 多克隆 anti-SCD antibody (ABIN569655) specifically detects SCD in IHC (p) 和 EIA. The antibody is reactive with 人 samples.
产品编号 ABIN569655
发货至: 中国
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Quick Overview for SCD 抗体 (C-Term) (ABIN569655)

抗原

See all SCD 抗体
SCD (Stearoyl-CoA Desaturase (Delta-9-Desaturase) (SCD))

适用

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宿主

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山羊

克隆类型

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多克隆

标记

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This SCD antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
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    C-Term

    特异性

    Recognizes Stearoyl-CoA desaturase.

    纯化方法

    Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide

    免疫原

    Peptide with sequence C-RIKRTGDGNYKSG, from the C Terminus of the protein sequence according to NP_005054.3.
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    Tris saline, pH ~7.3 with 0.02 % Sodium Azide and 0.5 % BSA

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    SCD (Stearoyl-CoA Desaturase (Delta-9-Desaturase) (SCD))

    别名

    SCD / SCD1

    背景

    Stearoyl-CoA desaturase (SCD, EC 1.14.99.5) is an iron-containing enzyme that catalyzes a rate-limiting step in the synthesis of unsaturated fatty acids. The principal product of SCD is oleic acid, which is formed by desaturation of stearic acid. The ratio of stearic acid to oleic acid has been implicated in the regulation of cell growth and differentiation through effects on cell membrane fluidity and signal transduction. Four SCD isoforms, Scd1 through Scd4, have been identified in mouse. In contrast, only 2 SCD isoforms, SCD1 and SCD5 (MIM 608370), have been identified in human. SCD1 shares about 85 % amino acid identity with all 4 mouse SCD isoforms, as well as with rat Scd1 and Scd2. In contrast, SCD5 shares limited homology with the rodent SCDs and appears to be unique to primates (Zhang et al. (1999) [PubMed 10229681], Wang et al., 2005).Synonyms: Acyl-CoA desaturase, Delta(9)-desaturase, Fatty acid desaturase, Stearoyl-CoA desaturase

    基因ID

    6319

    NCBI登录号

    NP_005054

    UniProt

    O00767

    途径

    Brown Fat Cell Differentiation
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