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PCBP1 抗体 (Internal Region)

The 山羊 多克隆 anti-PCBP1 antibody (ABIN569643) specifically detects PCBP1 in WB 和 EIA. The antibody is reactive with 人, 小鼠, 大鼠 和 犬 samples.
产品编号 ABIN569643
发货至: 中国
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Quick Overview for PCBP1 抗体 (Internal Region) (ABIN569643)

抗原

See all PCBP1 抗体
PCBP1 (Poly(rC) Binding Protein 1 (PCBP1))

适用

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  • 19
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  • 3
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  • 1
  • 1
人, 小鼠, 大鼠, 犬

宿主

  • 40
  • 9
  • 2
山羊

克隆类型

  • 31
  • 20
多克隆

标记

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  • 1
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  • 1
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This PCBP1 antibody is un-conjugated

应用范围

  • 44
  • 22
  • 12
  • 11
  • 5
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  • 3
  • 2
  • 1
Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 7
    • 5
    • 3
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    • 2
    • 1
    • 1
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    • 1
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    • 1
    AA 234-247, Internal Region

    序列

    C-ADLAKLNQVA RQQSH

    特异性

    Recognizes PCBP1 (234-247).

    交叉反应 (详细)

    Species reactivity (expected):Mouse, Rat, Canine (Dog).
    Species reactivity (tested):Human.

    纯化方法

    Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide

    免疫原

    Peptide with sequence from the internal region of the protein sequence according to NP_006187.2. Genename: PCBP1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    Tris saline, pH ~7.3 with 0.02 % Sodium Azide and 0.5 % BSA

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    PCBP1 (Poly(rC) Binding Protein 1 (PCBP1))

    别名

    PCBP1

    背景

    The protein encoded by this gene appears to be multifunctional. It along with PCBP-2 and hnRNPK corresponds to the major cellular poly(rC)-binding protein. It contains three K-homologous (KH) domains which may be involved in RNA binding. This encoded protein together with PCBP-2 also functions as translational coactivators of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES and promote poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human Papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability.Synonyms: Alpha-CP1, HNRPE1, HNRPX, Heterogeneous nuclear ribonucleoprotein E1, Nucleic acid-binding protein SUB2.3, Poly(rC)-binding protein 1, SUB2.3, hnRNP E1

    基因ID

    5093

    NCBI登录号

    NP_006187

    UniProt

    Q15365
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