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P5CS 抗体 (C-Term)

The 山羊 多克隆 anti-P5CS antibody (ABIN569586) specifically detects P5CS in WB 和 EIA. The antibody is reactive with 人, 小鼠, 大鼠, Cow, Pig 和 犬 samples.
产品编号 ABIN569586
发货至: 中国
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Quick Overview for P5CS 抗体 (C-Term) (ABIN569586)

抗原

See all P5CS (ALDH18A1) 抗体
P5CS (ALDH18A1) (Aldehyde Dehydrogenase 18 Family, Member A1 (ALDH18A1))

适用

  • 24
  • 8
  • 5
  • 3
  • 2
  • 2
  • 2
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  • 1
  • 1
人, 小鼠, 大鼠, Cow, Pig, 犬

宿主

  • 21
  • 4
  • 1
山羊

克隆类型

  • 24
  • 2
多克隆

标记

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  • 1
  • 1
  • 1
  • 1
  • 1
This P5CS antibody is un-conjugated

应用范围

  • 24
  • 15
  • 3
  • 2
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  • 1
Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 7
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    序列

    C-SEHGSLKYLH

    特异性

    This antibody is expected to recognize both reported isoforms of ALDH18A1 (NP_002851.2, NP_001017423.1).

    交叉反应 (详细)

    Species reactivity (expected):Rat, Canine (Dog), Cow, Pig.
    Species reactivity (tested):Human, Mouse.

    纯化方法

    Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.

    免疫原

    Peptide with sequence from the C Terminus of the protein sequence according to NP_002851.2, NP_001017423.1. Genename: ALDH18A1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    P5CS (ALDH18A1) (Aldehyde Dehydrogenase 18 Family, Member A1 (ALDH18A1))

    别名

    ALDH18A1

    背景

    Defects in ALDH18A1 are the cause of mental retardation-joint hypermobility-skin laxity with or without metabolic abnormalities (MRJHSL) [MIM:612652]. Clinical manifestations include microcephaly, progressive neurologic dysfunction, mental retardation, progeroid appearance, joint hypermobility, skin laxity and hyperelasticity, cataracts. Some patients manifest metabolic disturbances such as hyperammonemia, hypoornithinemia, hypocitrullinemia, hypoargininemia and hypoprolinemia.Synonyms: Aldehyde dehydrogenase family 18 member A1, Delta-1-pyrroline-5-carboxylate synthetase, GSAS, P5CS, PYCS

    分子量

    87.3kDa (NP_002851.2).

    基因ID

    5832

    NCBI登录号

    NP_001017423

    UniProt

    P54886
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