GRM2 抗体 (Internal Region)
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Quick Overview for GRM2 抗体 (Internal Region) (ABIN569585)
抗原
See all GRM2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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序列
- C-KETAPERREV
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特异性
- This antibody is expected to recognize both isoforms of GRM2 (NP_000830.2 and NP_001123535.1).
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交叉反应 (详细)
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Species reactivity (expected):Mouse, Rat, Canine (Dog), Bovine, Rabbit.
Species reactivity (tested):Human. -
纯化方法
- Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide
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免疫原
- Peptide with sequence from the internal region of Human GRM2 (NP_000830.2, NP_001123535.1). Genename: GRM2
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- GRM2 (Glutamate Receptor, Metabotropic 2 (GRM2))
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别名
- mGluR2 / GRM2
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背景
- The Metabotropic Glutamate Receptor GRM2 binds L-glutamate and has been linked to the inhibition of the cyclic AMP signaling cascade. GRM2 is involved in mediating the suppression of neurotransmission and in synaptogenesis and synaptic stabilization. Glutamatergic neurotransmission plays a role in most aspects of normal brain function and can be perturbed in many neuropathologic conditions.Synonyms: GPRC1B, Metabotropic glutamate receptor 2
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基因ID
- 2912
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NCBI登录号
- NP_000830
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UniProt
- Q14416
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途径
- cAMP Metabolic Process, Dicarboxylic Acid Transport
抗原
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