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- 抗原 See all DPYD 抗体
- DPYD (Dihydropyrimidine Dehydrogenase (DPYD))
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抗原表位
- AA 356-511
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This DPYD antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 交叉反应 （详细）
- No cross reactivity with other proteins.
- 产品特性
- Rabbit IgG polyclonal antibody for DPYD detection. Tested with WB, Direct ELISA in Human,Mouse,Rat.
- 免疫原
- E. coli-derived human DPYD recombinant protein (Position: A356-Y511).
- Top Product
- Discover our top product DPYD Primary Antibody
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anti-Dihydropyrimidine Dehydrogenase (DPYD) (AA 1-110) antibody
DPYD 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 7D4 unconjugated
anti-Dihydropyrimidine Dehydrogenase (DPYD) (Internal Region) antibodyDPYD 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Dihydropyrimidine Dehydrogenase (DPYD) (Internal Region) antibodyDPYD 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Dihydropyrimidine Dehydrogenase (DPYD) (AA 1-173) antibodyDPYD 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Dihydropyrimidine Dehydrogenase (DPYD) antibodyDPYD 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Dihydropyrimidine Dehydrogenase (DPYD) (AA 781-1025) antibodyDPYD 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Dihydropyrimidine Dehydrogenase (DPYD) (AA 841-875) antibodyDPYD 适用: 小鼠 WB 宿主: 兔 Polyclonal RB54986 unconjugated
anti-Dihydropyrimidine Dehydrogenase (DPYD) (AA 5-152) antibodyDPYD 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Dihydropyrimidine Dehydrogenase (DPYD) (AA 169-422) antibodyDPYD 适用: 小鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Dihydropyrimidine Dehydrogenase (DPYD) (AA 33-52) antibodyDPYD 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Recommended Detection Systems: Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.
Application Details: Western blot, 0.1-0.5 μg/mL
Direct ELISA, 0.1-0.5 μg/mL - 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
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- 抗原
- DPYD (Dihydropyrimidine Dehydrogenase (DPYD))
- 别名
- DPYD (DPYD 产品)
- 背景
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Synonyms: Dihydropyrimidine dehydrogenase [NADP(+)], DHPDHase, DPD, Dihydrothymine dehydrogenase, Dihydrouracil dehydrogenase, DPYD
Tissue Specificity: Found in most tissues with greatest activity found in liver and peripheral blood mononuclear cells.
Background: DPYD (Dihydropyrimidine Dehydrogenase), also called DPD, is an enzyme that in humans is encoded by the DPYD gene. The protein encoded by this gene is a pyrimidine catabolic enzyme and the initial and rate-limiting factor in the pathway of uracil and thymidine catabolism. The structure of the DPYD gene contains 23 exons spanning about 950 kb. Using somatic cell hybrid strategies, the DPYD gene is mapped to the centromeric region of chromosome 1 between 1p22 and 1q21. By fluorescence in situ hybridization, the DPYD gene is mapped to 1p22. The highest level of DPD was found in monocytes followed by that in lymphocytes, granulocytes, and platelets, whereas no significant activity of DPD could be detected in erythrocytes. The activity of DPD in peripheral blood mononuclear cells was intermediate between that observed in monocytes and lymphocytes. By cDNA microarray, Western blot analysis, and luciferase reporter assay, the transcription factor LSF was identified as a positive regulator of DPYD.
- UniProt
- Q12882
- 途径
- Ribonucleoside Biosynthetic Process
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