Periaxin 抗体 (AA 1-91) (DyLight 488)
Quick Overview for Periaxin 抗体 (AA 1-91) (DyLight 488) (ABIN7354670)
抗原
See all Periaxin (PRX) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-91
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原理
- Anti-Human PRX DyLight® 488 conjugated Antibody
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Anti-Human PRX DyLight® 488 conjugated Antibody (ABIN5693300)-Dyl488. Tested in Flow Cytometry applications. This antibody reacts with Human.
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免疫原
- E. coli-derived human PRX recombinant protein (Position: M1-K91).
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亚型
- IgG
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应用备注
- Flow Cytometry (Fixed), 1-3 μg/1x106 cells1. "Entrez Gene: PRX periaxin". 2. Gillespie CS, Sherman DL, Fleetwood-Walker SM, Cottrell DF, Tait S, Garry EM, Wallace VC, Ure J, Griffiths IR, Smith A, Brophy PJ (Jun 2000). "Peripheral demyelination and neuropathic pain behavior in periaxin-deficient mice". Neuron. 26 (2): 523-31.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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- Periaxin (PRX)
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别名
- PRX
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背景
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Synonyms: Periaxin, PRX, KIAA1620
Tissue Specificity: Detected in spinal cord (PubMed:11133365). Isoform 1 and isoform 2 are found in sciatic nerve and Schwann cells (PubMed:11157804).
Background: Periaxin is a protein that in humans is encoded by the PRX gene. This gene encodes a protein involved in peripheral nerve myelin upkeep. The encoded protein contains 2 PDZ domains which were named after PSD95 (post synaptic density protein), DlgA (Drosophila disc large tumor suppressor), and ZO1 (a mammalian tight junction protein). Two alternatively spliced transcript variants have been described for this gene which encode different protein isoforms and which are targeted differently in the Schwann cell. Mutations in this gene cause Charcot-Marie-Tooth neuoropathy, type 4F and Dejerine-Sottas neuropathy.
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分子量
- 39 kDa
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基因ID
- 57716
抗原
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