PI3 抗体 (AA 61-117)
Quick Overview for PI3 抗体 (AA 61-117) (ABIN5693295)
抗原
See all PI3 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 61-117
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原理
- Anti-Elafin/Skalp PI3 Antibody (monoclonal, C7)
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Elafin/Skalp PI3 Antibody Picoband® (monoclonal, C7) (ABIN5693295). Tested in ELISA, IHC applications. This antibody reacts with Human.
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免疫原
- E. coli-derived human Elafin/Skalp recombinant protein (Position: A61-Q117).
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亚型
- IgG1
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anti-Peptidase Inhibitor 3, Skin-Derived (PI3) (AA 1-117) antibody
PI3 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 2G20 unconjugated
anti-Peptidase Inhibitor 3, Skin-Derived (PI3) (AA 23-117) antibodyPI3 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Peptidase Inhibitor 3, Skin-Derived (PI3) antibodyPI3 适用: 人, 小鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Peptidase Inhibitor 3, Skin-Derived (PI3) (AA 1-117) antibodyPI3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3G9 unconjugated
anti-Peptidase Inhibitor 3, Skin-Derived (PI3) (AA 41-117) antibodyPI3 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Peptidase Inhibitor 3, Skin-Derived (PI3) (AA 1-117) antibodyPI3 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Peptidase Inhibitor 3, Skin-Derived (PI3) (AA 36-85) antibodyPI3 适用: 人, Cow WB 宿主: 兔 Polyclonal unconjugated
anti-Peptidase Inhibitor 3, Skin-Derived (PI3) (N-Term) antibodyPI3 适用: 人, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL
ELISA (Cap), 1-5 μg/mL1. "Entrez Gene: PI3 peptidase inhibitor 3, skin-derived (SKALP)". 2. Clauss A, Lilja H, Lundwall A (Nov 2002). "A locus on human chromosome 20 contains several genes expressing protease inhibitor domains with homology to whey acidic protein". Biochem J 368 (Pt 1): 233-42. 3. Molhuizen HO, Zeeuwen PL, Olde Weghuis D, Geurts van Kessel A, Schalkwijk J (Feb 1994). "Assignment of the human gene encoding the epidermal serine proteinase inhibitor SKALP (PI3) to chromosome region 20q12→q13". Cytogenet Cell Genet 66 (2): 129-31. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- PI3 (Peptidase Inhibitor 3, Skin-Derived (PI3))
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别名
- PI3
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背景
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Synonyms: Elafin, Elastase-specific inhibitor, ESI, Peptidase inhibitor 3, PI-3, Protease inhibitor WAP3, Skin-derived antileukoproteinase, SKALP, WAP four-disulfide core domain protein 14, PI3, WAP3, WFDC14
Tissue Specificity: Highly expressed in lung, spleen, heart, liver and kidney. Moderate levels in brain and skeletal muscle, and low in testis. Also found in many cell lines, highest expression in cells of the immune system.
Background: Elafin, also known as peptidase inhibitor 3 or skin-derived antileukoprotease (SKALP), is a protein that in humans is encoded by the PI3 gene. This gene encodes an elastase-specific inhibitor that functions as an antimicrobial peptide against Gram-positive and Gram-negative bacteria, and fungal pathogens. The protein contains a WAP-type four-disulfide core (WFDC) domain, and is thus a member of the WFDC domain family. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. And this gene belongs to the centromeric cluster. Expression of this gene is upgulated by bacterial lipopolysaccharides and cytokines.
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分子量
- 25 kDa
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基因ID
- 5266
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UniProt
- P19957
抗原
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