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WWOX 抗体 (AA 1-245)

Name: WWOX 抗体 (AA 1-245)
SKU: ABIN5693294
Availability: OutOfStock

WWOX 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC, FACS 宿主: 兔 Polyclonal unconjugated

Western blot analysis of WWOX using anti-WWOX antibody . (WWOX 抗体 (AA 1-245))

IHC analysis of WWOX using anti-WWOX antibody . (WWOX 抗体 (AA 1-245))

IHC

5 images

产品编号 ABIN5693294

发货至: 中国

Datasheet as PDF

抗原 See all WWOX 抗体

WWOX (WW Domain Containing Oxidoreductase (WWOX))
抗原表位
11

9

8

7

6

3

2

2

2

2

1

1

1

1

1

1

1

1
AA 1-245
适用
54

38

10

3

1

1

1

1

1

1

1

1
人, 小鼠, 大鼠
宿主
58

3

2
兔
Compatible Secondaries
克隆类型
61

2
多克隆
标记
40

4

3

2

2

2

2

2

2

2

1

1
This WWOX antibody is un-conjugated
应用范围
43

23

13

11

6

6

4

2

2

1

1

1

1

1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)

原理

Anti-WWOX Antibody Picoband®

交叉反应（详细）

No cross-reactivity with other proteins.

产品特性

Anti-WWOX Antibody Picoband® (ABIN5693294). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

免疫原

E. coli-derived human WWOX recombinant protein (Position: M1-D245).

亚型

IgG

Top Product

Discover our top product WWOX Primary Antibody
anti-WW Domain Containing Oxidoreductase (WWOX) (AA 1-180) antibody
WWOX 适用: 人 WB, ELISA, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated

anti-WW Domain Containing Oxidoreductase (WWOX) (AA 5-100) antibody
WWOX 适用: 人, 小鼠 WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-WW Domain Containing Oxidoreductase (WWOX) antibody
WWOX 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-WW Domain Containing Oxidoreductase (WWOX) (pTyr33) antibody
WWOX 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-WW Domain Containing Oxidoreductase (WWOX) (AA 1-189) antibody
WWOX 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated

anti-WW Domain Containing Oxidoreductase (WWOX) (N-Term) antibody
WWOX 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-WW Domain Containing Oxidoreductase (WWOX) (AA 1-120) antibody
WWOX 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-WW Domain Containing Oxidoreductase (WWOX) antibody
WWOX 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated

anti-WW Domain Containing Oxidoreductase (WWOX) (AA 1-186) antibody
WWOX 适用: 人 WB, IHC, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated

anti-WW Domain Containing Oxidoreductase (WWOX) (C-Term) antibody
WWOX 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

应用备注

Western blot, 0.1-0.5 μg/mL
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL
Immunocytochemistry/Immunofluorescence, 2 μg/mL
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells
ELISA, 0.1-0.5 μg/mL
1. "Entrez Gene: WWOX WW domain containing oxidoreductase". 2. Bednarek AK, Laflin KJ, Daniel RL, Liao Q, Hawkins KA, Aldaz CM (May 2000). "WWOX, a novel WW domain-containing protein mapping to human chromosome 16q23.3-24.1, a region frequently affected in breast cancer". Cancer Res. 60 (8): 2140-5. 3. Mahajan NP, Whang YE, Mohler JL, Earp HS (November 2005). "Activated tyrosine kinase Ack1 promotes prostate tumorigenesis: role of Ack1 in polyubiquitination of tumor suppressor Wwox.". Cancer Res. 65 (22): 10514-23.

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
抗原

WWOX (WW Domain Containing Oxidoreductase (WWOX))

别名

WWOX (WWOX 产品)

背景

Synonyms: WW domain-containing oxidoreductase, Fragile site FRA16D oxidoreductase, Short chain dehydrogenase/reductase family 41C member 1, WWOX, FOR, SDR41C1, WOX1
Tissue Specificity: Widely expressed. Strongly expressed in testis, prostate, and ovary. Overexpressed in cancer cell lines. Isoform 5 and isoform 6 may only be expressed in tumor cell lines.
Background: WW domain-containing oxidoreductase is an enzyme that in humans is encoded by the WWOX gene. This gene encodes a member of the short-chain dehydrogenases/reductases (SDR) protein family. It spans the FRA16D common chromosomal fragile site and appears to function as a tumor suppressor gene. Expression of the encoded protein is able to induce apoptosis, while defects in this gene are associated with multiple types of cancer. Disruption of this gene is also associated with autosomal recessive spinocerebellar ataxia 12. Disruption of a similar gene in mouse results in impaired steroidogenesis, additionally suggesting a metabolic function for the protein. Alternative splicing results in multiple transcript variants.

分子量

46 kDa

基因ID

51741