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TPR 抗体

TPR 适用: 人, 小鼠, 大鼠 WB, IHC, ICC, IF, IHC (fro), FACS 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5693275
发货至: 中国
  • 抗原 See all TPR 抗体
    TPR (Nucleoprotein TPR (TPR))
    适用
    • 23
    • 20
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    人, 小鼠, 大鼠
    宿主
    • 35
    • 2
    克隆类型
    • 35
    • 2
    多克隆
    标记
    • 17
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TPR antibody is un-conjugated
    应用范围
    • 13
    • 12
    • 12
    • 7
    • 6
    • 6
    • 5
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro)), Flow Cytometry (FACS)
    原理
    Anti-TPR Antibody Picoband®
    序列
    MLQAEKKLLE EDVKRWKARN QHLVSQQKD
    交叉反应 (详细)
    No cross-reactivity with other proteins.
    产品特性
    Anti-TPR Antibody Picoband® (ABIN5693275). Tested in Flow Cytometry, IF, IHC, IHC-F, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
    免疫原
    A synthetic peptide corresponding to a sequence in the middle region of human TPR, which shares 89.7% and 93.1% amino acid (aa) sequence identity with mouse and rat TPR, respectively.
    亚型
    IgG
    Top Product
    Discover our top product TPR Primary Antibody
  • 应用备注
    Western blot, 0.1-0.5 μg/mL
    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL
    Immunohistochemistry (Frozen Section), 0.5-1 μg/mL
    Immunocytochemistry/Immunofluorescence, 2 μg/mL
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells
    1. Gonzatti-Haces, M., Seth, A., Park, M., Copeland, T., Oroszlan, S., Vande Woude, G. F. Characterization of the TPR-MET oncogene p65 and the MET protooncogene p140 protein-tyrosine kinases. Proc. Nat. Acad. Sci. 85: 21-25, 1988. 2. Miranda, C., Minoletti, F., Greco, A., Sozzi, G., Pierotti, M. A. Refined localization of the human TPR gene to chromosome 1q25 by in situ hybridization. Genomics 23: 714-715, 1994.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原
    TPR (Nucleoprotein TPR (TPR))
    别名
    TPR (TPR 产品)
    背景

    Synonyms: Nucleoprotein TPR, Megator, NPC-associated intranuclear protein, Translocated promoter region protein, TPR

    Tissue Specificity: Expressed in esophagus, ovary, liver, skin, smooth muscles, cerebrum and fetal cerebellum (at protein level). Highest in testis, lung, thymus, spleen and brain, lower levels in heart, liver and kidney.

    Background: The tetratricopeptide repeat (TPR) is a structural motif. This gene encodes a large coiled-coil protein that forms intranuclear filaments attached to the inner surface of nuclear pore complexes (NPCs). The protein ly interacts with several components of the NPC. It is required for the nuclear export of mRNAs and some proteins. Oncogenic fusions of the 5' end of this gene with several different kinase genes occur in some neoplasias.

    分子量
    300 kDa
    基因ID
    7175
    UniProt
    P12270
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