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GALE 抗体 (AA 1-340)

Name: GALE 抗体 (AA 1-340)
SKU: ABIN5693266
Availability: OutOfStock

GALE 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

Western blot analysis of GALE using anti-GALE antibody . (GALE 抗体 (AA 1-340))

IHC analysis of GALE using anti-GALE antibody . (GALE 抗体 (AA 1-340))

IHC

6 images

产品编号 ABIN5693266

发货至: 中国

Datasheet as PDF

抗原 See all GALE 抗体

GALE (UDP-Galactose-4-Epimerase (GALE))
抗原表位
14

10

7

2

2

1

1
AA 1-340
适用
34

17

5

3

2

2

2

1

1

1
人, 小鼠, 大鼠
宿主
44

4
兔
Compatible Secondaries
克隆类型
46

2
多克隆
标记
20

4

3

3

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This GALE antibody is un-conjugated
应用范围
38

16

12

12

6

5

5

3

1

1

1

1

1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

原理

Anti-GALE Antibody Picoband®

交叉反应（详细）

No cross-reactivity with other proteins.

产品特性

Anti-GALE Antibody Picoband® (ABIN5693266). Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

免疫原

E. coli-derived human GALE recombinant protein (Position: M1-N340).

亚型

IgG

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anti-UDP-Galactose-4-Epimerase (GALE) antibody
GALE 适用: 人, 大鼠, 犬, 猴 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 1C4 unconjugated

anti-UDP-Galactose-4-Epimerase (GALE) (AA 1-348) antibody
GALE 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-UDP-Galactose-4-Epimerase (GALE) (AA 142-171) antibody
GALE 适用: 人 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB21189 unconjugated

anti-UDP-Galactose-4-Epimerase (GALE) (AA 1-348) antibody
GALE 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated

anti-UDP-Galactose-4-Epimerase (GALE) (AA 1-348) antibody
GALE 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated

anti-UDP-Galactose-4-Epimerase (GALE) (AA 129-348) antibody
GALE 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-UDP-Galactose-4-Epimerase (GALE) (N-Term) antibody
GALE 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-UDP-Galactose-4-Epimerase (GALE) (Middle Region) antibody
GALE 适用: 人, 大鼠, 犬, Cow, Pig, 兔, 马 WB 宿主: 兔 Polyclonal unconjugated

anti-UDP-Galactose-4-Epimerase (GALE) antibody
GALE 适用: 人 WB, IF, IC 宿主: 兔 Polyclonal unconjugated

anti-UDP-Galactose-4-Epimerase (GALE) (AA 21-120) antibody
GALE 适用: 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated

应用备注

Western blot, 0.1-0.5 μg/mL
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL
ELISA, 0.1-0.5 μg/mL
1. Maceratesi, P., Daude, N., Dallapiccola, B., Novelli, G., Allen, R., Okano, Y., Reichardt, J.Human UDP-galactose 4-prime epimerase (GALE) gene and identification of five missense mutations in patients with epimerase-deficiency galactosemia. Molec. Genet. Metab. 63: 26-30, 1998. 2. Thoden JB, Wohlers TM, Fridovich-Keil JL, Holden HM (May 2001). "Human UDP-galactose 4-epimerase. Accommodation of UDP-N-acetylglucosamine within the active site". J. Biol. Chem. 276 (18): 15131-6.

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
抗原

GALE (UDP-Galactose-4-Epimerase (GALE))

别名

GALE (GALE 产品)

背景

Synonyms: UDP-glucose 4-epimerase
Tissue Specificity: Colocalizes with SMARCA4/BRG1 in E-cadherin-negative cells from established lines, and stroma of normal colon as well as in de-differentiated epithelial cells at the invasion front of colorectal carcinomas (at protein level). Expressed in heart and skeletal muscle, but not in liver, spleen, or pancreas.
Background: The enzyme UDP-glucose 4-epimerase, also known as UDP-galactose 4-epimerase or GALE, is a homodimeric epimerase found in bacterial, fungal, plant, and mammalian cells. This gene encodes UDP-galactose-4-epimerase which catalyzes two distinct but analogous reactions: the epimerization of UDP-glucose to UDP-galactose, and the epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine. The bifunctional nature of the enzyme has the important metabolic consequence that mutant cells (or individuals) are dependent not only on exogenous galactose, but also on exogenous N-acetylgalactosamine as a necessary precursor for the synthesis of glycoproteins and glycolipids. Mutations in this gene result in epimerase-deficiency galactosemia, also referred to as galactosemia type 3, a disease characterized by liver damage, early-onset cataracts, deafness and mental retardation, with symptoms ranging from mild ('peripheral' form) to severe ('generalized' form). Multiple alternatively spliced transcripts encoding the same protein have been identified.

分子量

38 kDa

基因ID

2582

UniProt

Q14376

途径

Response to Water Deprivation, Cellular Glucan Metabolic Process