MUC6 抗体 (AA 52-230)
Quick Overview for MUC6 抗体 (AA 52-230) (ABIN5693243)
抗原
See all MUC6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 52-230
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原理
- Anti-Gastric Mucin/MUC6 Antibody Picoband®
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Anti-Gastric Mucin/MUC6 Antibody Picoband® (ABIN5693243). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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免疫原
- E. coli-derived human Gastric Mucin recombinant protein (Position: H52-R230).
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亚型
- IgG
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应用备注
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Western blot, 0.1-0.5 μg/mL
ELISA, 0.1-0.5 μg/mL
1. Kwon, J.-A., Lee, S.-Y., Ahn, E.-K., Seol, S.-Y., Kim, M. C., Kim, S. J., Kim, S. I., Chu, I.-S., Leem, S.-H. Short rare MUC6 minisatellites-5 (sic) alleles influence susceptibility to gastric carcinoma by regulating gene expression. Hum. Mutat. 31: 942-949, 2010. 2. Toribara, N. W., Roberton, A. M., Ho, S. B., Kuo, W.-L., Gum, E., Hicks, J. W., Gum, J. R., Jr., Byrd, J. C., Siddiki, B., Kim, Y. S. Human gastric mucin: identification of a unique species by expression cloning. J. Biol. Chem. 268: 5879-5885, 1993. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- MUC6 (Mucin 6, Oligomeric Mucus/gel-Forming (MUC6))
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别名
- MUC6
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背景
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Synonyms: Mucin-6, MUC-6, Gastric mucin-6, MUC6
Tissue Specificity: Expressed in the regenerative zone of gastric antrum, gastric body mucosa and gastric incisura mucosa. Expressed in the deeper mucous glands of gastric antrum. Overexpressed in Helicobacter pylori infected gastric epithelium. Highly expressed in duodenal Brunner's glands, gall bladder, seminal vesicle, pancreatic centroacinar cells and ducts, and periductal glands of the common bile duct.
Background: Mucin 6, oligomeric mucus/gel-forming, also known as MUC6, is a human gene. This gene encodes a member of the mucin protein family. Mucins are high molecular weight glycoproteins produced by many epithelial tissues. The protein encoded by this gene is secreted and forms an insoluble mucous barrier that protects the gut lumen. The MUC6 gene encodes gastric mucin, a secreted glycoprotein that plays an essential role in epithelial cytoprotection from acid, proteases, pathogenic microorganisms, and mechanical trauma in the gastrointestinal tract.
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分子量
- 257 kDa
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基因ID
- 4588
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UniProt
- Q6W4X9
抗原
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