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HSP70 1A 抗体 (C-Term)

HSPA1A 适用: 人, 小鼠, 大鼠 WB, ICC, IHC (p), FACS, IHC (fro) 宿主: 小鼠 Monoclonal 3H5 unconjugated
产品编号 ABIN5693238
发货至: 中国
  • 抗原 See all HSP70 1A (HSPA1A) 抗体
    HSP70 1A (HSPA1A) (Heat Shock 70kDa Protein 1A (HSPA1A))
    抗原表位
    • 12
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    AA 559-596, C-Term
    适用
    • 125
    • 31
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    人, 小鼠, 大鼠
    宿主
    • 87
    • 56
    小鼠
    克隆类型
    • 85
    • 58
    单克隆
    标记
    • 70
    • 17
    • 15
    • 7
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    • 1
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    This HSP70 1A antibody is un-conjugated
    应用范围
    • 125
    • 56
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    • 12
    • 6
    • 5
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))
    品牌
    Picoband™
    序列
    KGKISEADKK KVLDKCQEVI SWLDANTLAE KDEFEHKR
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Mouse IgG monoclonal antibody for Hsp70 detection. Tested with WB, IHC-P, IHC-F, ICC, FCM in Human,Mouse,Rat.
    免疫原
    A synthetic peptide corresponding to a sequence at the C-terminus of human Hsp70 (559-596aa KGKISEADKKKVLDKCQEVISWLDANTLAEKDEFEHKR), different from the related mouse sequence by five amino acids, and from the related rat sequence by three amino acids.
    克隆位点
    3H5
    亚型
    IgG1
    Top Product
    Discover our top product HSPA1A Primary Antibody
  • 应用备注

    Recommended Detection Systems: Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P), IHC(F) and ICC.

    Application Details: Western blot, 0.1-0.5 μg/mL
    Immunohistochemistry(Paraffin-embedded Section), 0.5-1 μg/mL
    Immunohistochemistry(Frozen Section), 0.5-1 μg/mL
    Immunocytochemistry, 0.5-1 μg/mL
    Flow Cytometry, 1-3 μg/1x106 cells

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    缓冲液
    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存方法
    At -20℃, for one year. After reconstitution, at 4℃, for one month.
    It can also be aliquotted and stored frozen at -20℃, for a longer time. Avoid repeated freezing and thawing.
  • Zhang, Tang, Li, Li, Zhang, Yan, Cui: "Effects of intracerebral hemorrhage and subsequent minimally invasive hematoma aspiration on expression of apoptosisrelated genes in rats." in: International journal of clinical and experimental pathology, Vol. 8, Issue 5, pp. 5371-8, (2016) (PubMed).

    Pu, Shi, Wang, Wang, Guo, Liu, Sun, Gao, Zhou: "Effects of minocycline on the expression of NGF and HSP70 and its neuroprotection role following intracerebral hemorrhage in rats." in: Journal of biomedical research, Vol. 25, Issue 4, pp. 292-8, (2013) (PubMed).

    Li, Roubeix, Wang, Shi, Liu, Baudouin, Chen: "Therapeutic efficacy of trehalose eye drops for treatment of murine dry eye induced by an intelligently controlled environmental system." in: Molecular vision, Vol. 18, pp. 317-29, (2012) (PubMed).

    Yi, Peng, Chang, Peng, Yan, Lin: "Effect of pre-moxibustion on apoptosis and proliferation of gastric mucosa cells." in: World journal of gastroenterology, Vol. 13, Issue 15, pp. 2174-8, (2007) (PubMed).

    Wu, Cao, Gao, Chen, Wang, Zumbika, Qian: "Down-modulation of heat shock protein 70 and up-modulation of Caspase-3 during schisandrin B-induced apoptosis in human hepatoma SMMC-7721 cells." in: World journal of gastroenterology, Vol. 10, Issue 20, pp. 2944-8, (2004) (PubMed).

  • 抗原
    HSP70 1A (HSPA1A) (Heat Shock 70kDa Protein 1A (HSPA1A))
    别名
    HSPA1A (HSPA1A 产品)
    别名
    hsp70-4 antibody, hspa1a antibody, Hsp70-3 antibody, Hsp70.3 antibody, Hsp72 antibody, hsp68 antibody, hsp70A1 antibody, HSP72 antibody, Hsp70-1 antibody, Hspa1 antibody, Hspa1b antibody, hsp70-1 antibody, hsp70-1a antibody, hsp70i antibody, hsp72 antibody, hspa1 antibody, hspa1b antibody, HSP70-1 antibody, HSP70-1A antibody, HSP70I antibody, HSPA1 antibody, HSPA1A antibody, HSPA1B antibody, HSP70-2 antibody, HSPA2 antibody, HSP70 antibody, hspA1A antibody, heat shock cognate 70-kd protein, tandem duplicate 3 antibody, heat shock 70 kDa protein 1 antibody, heat shock 70 kDa protein II antibody, heat shock protein 1A antibody, heat shock 70kD protein 1A antibody, heat shock protein family A (Hsp70) member 1A S homeolog antibody, heat shock protein family A (Hsp70) member 1A antibody, heat shock protein 70.2 antibody, heat shock 70kDa protein 1A antibody, heat shock 70 kDa protein 1B antibody, heat shock protein 70.1 antibody, hsp70.3 antibody, LOC100023597 antibody, LOC100554002 antibody, LOC100608888 antibody, Hspa1a antibody, hspa1a.S antibody, HSPA1A antibody, HSP70.2 antibody, LOC100354037 antibody, HSP70.1 antibody
    背景

    Synonyms: Heat shock 70 kDa protein 1A, Heat shock 70 kDa protein 1B

    Background: HSPA1 (heat shock 70  kDa protein 1A) also known as HSP70-1, HSPA1A, HSP70-1A, HSP72 or HSP70I, is a protein that in humans is encoded by the HSPA1A gene. This intronless gene encodes a 70  kDa heat shock protein which is a member of the heat shock protein 70 family. The HSPA1A gene encodes a predicted 641-amino acid protein. The HSPA1 gene is mapped on 6p21.33. Shimizu et al. (1999) found that peripheral blood mononuclear cells of 18 major depression patients expressed a short HSPA1A transcript that utilized exon 1 rather than exon 2, which is found in the more common HSPA1A transcript. No protein was associated with expression of this short HSPA1A mRNA, possibly due to lack of a TATA box or loss of internal ribosome binding sites. Treatment with BGP-15, a pharmacologic inducer of Hsp72 that can protect against obesity-induced insulin resistance, improved muscular architecture, strength, and contractile function in severely affected diaphragm muscles in mdx dystrophic mice.

    途径
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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