GSTM1 抗体
Quick Overview for GSTM1 抗体 (ABIN5693233)
抗原
See all GSTM1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-GSTM1 Antibody Picoband® (monoclonal, 11F2)
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序列
- EEEKIRVDIL ,ENQTMDNHMQ LGMICYNPEF EKLK
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-GSTM1 Antibody Picoband® (monoclonal, 11F2) (ABIN5693233). Tested in Flow Cytometry, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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免疫原
- A synthetic peptide corresponding to a sequence in the middle region of human GSTM1, which shares 70.6% and 73.5% amino acid (aa) sequence identity with mouse and rat GSTM1, respectively.
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亚型
- IgG1
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anti-Glutathione S-Transferase mu 1 (GSTM1) antibody
GSTM1 适用: 人, 猴 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 1H4A4 unconjugated
anti-Glutathione S-Transferase mu 1 (GSTM1) (AA 1-218) antibodyGSTM1 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Glutathione S-Transferase mu 1 (GSTM1) (AA 1-218) antibodyGSTM1 适用: 大鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Glutathione S-Transferase mu 1 (GSTM1) antibodyGSTM1 适用: 人 WB, IHC, StM 宿主: 小鼠 Monoclonal CPTC-GSTMu1-3 unconjugated
anti-Glutathione S-Transferase mu 1 (GSTM1) (AA 1-218) antibodyGSTM1 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Glutathione S-Transferase mu 1 (GSTM1) (AA 24-156) antibodyGSTM1 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Glutathione S-Transferase mu 1 (GSTM1) (AA 184-211), (C-Term) antibodyGSTM1 适用: 人, 小鼠 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB21078 unconjugated
anti-Glutathione S-Transferase mu 1 (GSTM1) (C-Term) antibodyGSTM1 适用: 人, 小鼠, 大鼠, 犬, Cow, 兔, Pig WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Glutathione S-Transferase mu 1 (GSTM1) (AA 1-220) antibodyGSTM1 适用: 小鸡 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Glutathione S-Transferase mu 1 (GSTM1) (AA 31-80) antibodyGSTM1 适用: 人, 小鼠, 大鼠, 犬, Cow, 兔, 豚鼠, 马, 猴, Bat, Hamster WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL
Immunohistochemistry (Frozen Section), 0.5-1 μg/mL
Immunocytochemistry, 0.5-1 μg/mL
Flow Cytometry (Fixed), 1-3 μg/1x106 cells
1. Carless, M. A., Lea, R. A., Curran, J. E., Appleyard, B., Gaffney, P., Green, A., Griffiths, L. R. TheGSTM1 null genotype confers an increased risk for solar keratosis development in an Australian Caucasian population. J. Invest. Derm. 119: 1373-1378, 2002. 2. Zhong, S., Wyllie, A. H., Barnes, D., Wolf, C. R., Spurr, N. K. Relationship between theGSTM1 genetic polymorphism and susceptibility to bladder, breast and colon cancer.Carcinogenesis 14: 1821-1824, 1993. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- GSTM1 (Glutathione S-Transferase mu 1 (GSTM1))
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别名
- GSTM1
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背景
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Synonyms: Glutathione S-transferase Mu 1, GST HB subunit 4, GST class-mu 1, GSTM1-1, GSTM1a-1a, GSTM1b-1b, GTH4, GSTM1, GST1
Tissue Specificity: Liver (at protein level).
Background: Glutathione S-transferase Mu 1 (gene name GSTM1) is a human glutathione S-transferase. Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Null mutations of this class mu gene have been linked with an increase in a number of cancers, likely due to an increased susceptibility to environmental toxins and carcinogens. Multiple protein isoforms are encoded by transcript variants of this gene.
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分子量
- 26 kDa
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基因ID
- 2944
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UniProt
- P09488
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途径
- Negative Regulation of Transporter Activity
抗原
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