RNASE3 抗体 (AA 28-160)
Quick Overview for RNASE3 抗体 (AA 28-160) (ABIN5693221)
抗原
See all RNASE3 (ECP) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 28-160
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原理
- Anti-Ribonuclease 3/RNASE3 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Ribonuclease 3/RNASE3 Antibody Picoband® (ABIN5693221). Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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免疫原
- E. coli-derived human Ribonuclease 3 recombinant protein (Position: R28-I160).
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亚型
- IgG
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anti-Eosinophil Cationic Protein (ECP) (AA 30-154) antibody
ECP 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Eosinophil Cationic Protein (ECP) (AA 33-155) antibodyECP 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Eosinophil Cationic Protein (ECP) (AA 30-154) antibodyECP 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C3 unconjugated
anti-Eosinophil Cationic Protein (ECP) (AA 34-150) antibodyECP 适用: 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Eosinophil Cationic Protein (ECP) (AA 30-154) antibodyECP 适用: 人 WB 宿主: 小鼠 Monoclonal C5 unconjugated
anti-Eosinophil Cationic Protein (ECP) (AA 28-160) antibodyECP 适用: 人 IHC 宿主: 兔 Polyclonal unconjugated
anti-Eosinophil Cationic Protein (ECP) (AA 124-151) antibodyECP 适用: 人 WB, IF 宿主: 兔 Polyclonal RB30251 unconjugated
anti-Eosinophil Cationic Protein (ECP) (AA 28-160) antibodyECP 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Eosinophil Cationic Protein (ECP) (AA 124-151), (C-Term) antibodyECP 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL
ELISA, 0.1-0.5 μg/mL
1. Mastrianni DM, Eddy RL, Rosenberg HF, Corrette SE, Shows TB, Tenen DG, Ackerman SJ (May 1992). "Localization of the human eosinophil Charcot-Leyden crystal protein (lysophospholipase) gene (CLC) to chromosome 19 and the human ribonuclease 2 (eosinophil-derived neurotoxin) and ribonuclease 3 (eosinophil cationic protein) genes (RNS2 and RNS3) to chromosome 14". Genomics. 13 (1): 240-2. 2. Rosenberg, H. F., Ackerman, S. J., Tenen, D. G. Human eosinophil cationic protein: molecular cloning of a cytotoxin and helminthotoxin with ribonuclease activity. J. Exp. Med. 170: 163-176, 1989. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- RNASE3 (ECP) (Eosinophil Cationic Protein (ECP))
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别名
- RNASE3
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背景
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Synonyms: Eosinophil cationic protein, ECP, Ribonuclease 3, RNase 3, RNASE3, ECP, RNS3
Tissue Specificity: Mainly expressed in pachytene spermatocytes of testis and in lymphocyte-rich areas of spleen and lymph nodes. Isoform v1 is expressed in spleen. Isoform v2 is expressed in testis. Also detected in ovary, placenta, pancreas, cardiac fibroblasts. Expressed in B-cells and prostate malignant cells. Isoform v1 and isoform v3 are expressed in epithelial colorectal adenocarcinoma cells. Isoform v2 and isoform v4 are expressed in endothelial cells. Isoform v1, isoform v2, isoform v3 and isoform v4 are expressed in pulmonary artery smooth muscle cells. Isoform v2 and isoform v5 are expressed in microvascular endothelial cells (at protein level).
Background: Eosinophil Cationic Protein (ECP) also known as ribonuclease 3 is a basic protein located in the eosinophil primary matrix. In humans, the eosinophil cationic protein is encoded by the RNASE3 gene. The protein encoded by this gene belongs to the pancreatic ribonuclease family, a subset of the ribonuclease A superfamily. ECP is released during degranulation of eosinophils. This protein is related to inflammation and asthma because in these cases, there are increased levels of ECP in the body.
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分子量
- 18 kDa
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基因ID
- 6037
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UniProt
- P12724
抗原
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