EOMES 抗体 (AA 310-532)
Quick Overview for EOMES 抗体 (AA 310-532) (ABIN5693217)
抗原
See all EOMES 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 310-532
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原理
- Anti-TBR2/Eomes Antibody Picoband®
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Anti-TBR2/Eomes Antibody Picoband® (ABIN5693217). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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免疫原
- E. coli-derived human TBR2/Eomes recombinant protein (Position: T310-D532).
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亚型
- IgG
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应用备注
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Western blot, 0.1-0.5 μg/mL
ELISA, 0.1-0.5 μg/mL
1. Arnold SJ, Huang GJ, Cheung AF, Era T, Nishikawa S, Bikoff EK, Molnár Z, Robertson EJ, Groszer M (2008). "The T-box transcription factor Eomes/Tbr2 regulates neurogenesis in the cortical subventricular zone". Genes & Development. 22 (18): 2479-84. 2. Sessa A, Mao CA, Hadjantonakis AK, Klein WH, Broccoli V (Oct 2008). "Tbr2 s conversion of radial glia into basal precursors and guides neuronal amplification by in neurogenesis in the developing neocortex glish". Neuron. 60 (1): 56-69. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- EOMES (Eomesodermin (EOMES))
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别名
- EOMES
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背景
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Synonyms: Eomesodermin homolog, T-box brain protein 2, T-brain-2, TBR-2, EOMES, TBR2
Tissue Specificity: Expressed in CD8+ T-cells.
Background: Eomesodermin also known as T-box brain protein 2 (Tbr2) is a protein that in humans is encoded by the EOMES gene. This gene belongs to the TBR1 (T-box brain protein 1) sub-family of T-box genes that share the common DNA-binding T-box domain. The encoded protein is a transcription factor which is crucial for embryonic development of mesoderm and the central nervous system in vertebrates. The protein may also be necessary for the differentiation of effector CD8+ T cells which are involved in defense against viral infections. A similar gene disrupted in mice is shown to be essential during trophoblast development and gastrulation. Alternative splicing results in multiple transcript variants.
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分子量
- 85 kDa
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基因ID
- 8320
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UniProt
- O95936
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途径
- Stem Cell Maintenance
抗原
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