APCS 抗体 (AA 20-220)
Quick Overview for APCS 抗体 (AA 20-220) (ABIN5693182)
抗原
See all APCS 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 20-220
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原理
- Anti-Serum Amyloid P/APCS Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Serum Amyloid P/APCS Antibody Picoband® (ABIN5693182). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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免疫原
- E. coli-derived human Serum Amyloid P recombinant protein (Position: H20-L220).
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亚型
- IgG
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anti-Amyloid P Component, Serum (APCS) (AA 23-223) antibody
APCS 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Amyloid P Component, Serum (APCS) (AA 22-222) antibodyAPCS 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Amyloid P Component, Serum (APCS) (AA 1-223) antibodyAPCS 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Amyloid P Component, Serum (APCS) (AA 143-223) antibodyAPCS 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal APCS-3240 unconjugated
anti-Amyloid P Component, Serum (APCS) (AA 35-149) antibodyAPCS 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4F3 unconjugated
anti-Amyloid P Component, Serum (APCS) (AA 117-223) antibodyAPCS 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Amyloid P Component, Serum (APCS) antibodyAPCS 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Amyloid P Component, Serum (APCS) antibodyAPCS 适用: 人 WB, IF 宿主: 小鼠 Monoclonal 5A9 unconjugated
anti-Amyloid P Component, Serum (APCS) (AA 117-223) antibodyAPCS 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4E8 unconjugated
anti-Amyloid P Component, Serum (APCS) (Internal Region) antibodyAPCS 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL
Immunocytochemistry/Immunofluorescence, 5 μg/mL
Flow Cytometry (Fixed), 1-3 μg/1x106 cells
ELISA, 0.1-0.5 μg/mL
1. Cathcart ES, Shirahama T, Cohen AS (1967). "Isolation and identification of a plasma component of amyloid". Biochim. Biophy. Acta 147: 392-393. 2. "Entrez Gene: APCS amyloid P component, serum". 3. Emsley J, White HE, O'Hara BP, Oliva G, Srinivasan N, Tickle IJ, Blundell TL, Pepys MB, Wood SP (1994). "Structure of pentameric human serum amyloid P component". Nature 367 (6461): 338-45. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- APCS (Amyloid P Component, Serum (APCS))
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别名
- APCS
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背景
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Synonyms: Serum amyloid P-component; SAP; 9.5S alpha-1-glycoprotein; Serum amyloid P-component (1-203); APCS; PTX2
Tissue Specificity: Found in serum and urine.
Background: Amyloid P component, serum (SAP), also known as PTX2 or APCS, is the identical serum form of amyloid P component (AP), a 25kDa pentameric protein first identified as the pentagonal constituent of in vivo pathological deposits called "amyloid". It belongs to the pentraxins family, characterised by calcium dependent ligand binding and distinctive flattened β-jellyroll structure similar to that of the legume lectins. This gene is mapped to 1q23.2. The binding of the encoded protein to proteins in the pathological amyloid cross-beta fold suggests its possible role as a chaperone. This protein is also thought to control the degradation of chromatin. It has been demonstrated that this protein binds to apoptotic cells at an early stage, which raises the possibility that it is involved in dealing with apoptotic cells in vivo.
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分子量
- 25-29 kDa
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基因ID
- 325
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UniProt
- P02743
抗原
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