ESRRG 抗体 (AA 302-458)
Quick Overview for ESRRG 抗体 (AA 302-458) (ABIN5693179)
抗原
See all ESRRG 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 302-458
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原理
- Anti-strogen Related Receptor gamma/ESRRG Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-strogen Related Receptor gamma/ESRRG Antibody Picoband® (ABIN5693179). Tested in ELISA, Flow Cytometry, IF, IHC, IHC-F, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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免疫原
- E. coli-derived human ESRRG recombinant protein (Position: Q302-V458).
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亚型
- IgG
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anti-Estrogen-Related Receptor gamma (ESRRG) (AA 24-263) antibody
ESRRG 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 6G1 unconjugated
anti-Estrogen-Related Receptor gamma (ESRRG) (Middle Region) antibodyESRRG 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 兔, 斑马鱼, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Estrogen-Related Receptor gamma (ESRRG) antibodyESRRG 适用: 人 WB, IHC (wm) 宿主: 兔 Polyclonal unconjugated
anti-Estrogen-Related Receptor gamma (ESRRG) (N-Term) antibodyESRRG 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 兔, 斑马鱼, 猴, Bat, 小鸡, 非洲爪蟾, Hamster IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Estrogen-Related Receptor gamma (ESRRG) (N-Term) antibodyESRRG 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 兔, 猴, Bat, Hamster ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Estrogen-Related Receptor gamma (ESRRG) (Internal Region) antibodyVerified ESRRG 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Estrogen-Related Receptor gamma (ESRRG) (C-Term) antibodyESRRG 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 兔, 猴, 小鸡, Pig, Hamster WB, IHC, IHC (p), ChIP 宿主: 兔 Polyclonal unconjugated
anti-Estrogen-Related Receptor gamma (ESRRG) (AA 190-239) antibodyESRRG 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 兔, 斑马鱼, 豚鼠, 猴, Bat, 小鸡, Pig, 非洲爪蟾 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Estrogen-Related Receptor gamma (ESRRG) (AA 24-263) antibodyESRRG 适用: 人 WB, IF 宿主: 小鼠 Monoclonal 1D10 unconjugated
anti-Estrogen-Related Receptor gamma (ESRRG) (AA 61-160) antibodyESRRG 适用: 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL
Immunohistochemistry (Frozen Section), 0.5-1 μg/mL
Immunocytochemistry/Immunofluorescence, 2 μg/mL
Flow Cytometry (Fixed), 1-3 μg/1x106 cells
ELISA, 0.1-0.5 μg/mL
1. "Entrez Gene: ESRRG estrogen-related receptor gamma". 2. Matsushima A, Kakuta Y, Teramoto T, Koshiba T, Liu X, Okada H, Tokunaga T, Kawabata S, Kimura M, Shimohigashi Y (Oct 2007). "Structural evidence for endocrine disruptor bisphenol A binding to human nuclear receptor ERR gamma". Journal of Biochemistry. 142 (4): 517-24. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- ESRRG (Estrogen-Related Receptor gamma (ESRRG))
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别名
- ESRRG
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背景
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Synonyms: Estrogen-related receptor gamma, ERR gamma-2, Estrogen receptor-related protein 3, Nuclear receptor subfamily 3 group B member 3, ESRRG, ERR3, ERRG2, KIAA0832, NR3B3
Tissue Specificity: Expressed in the heart, kidney, brain, lung, bone marrow, adrenal gland, trachea, spinal cord and thyroid gland.
Background: Estrogen-related receptor gamma (ERR-gamma), also known as NR3B3, is a nuclear receptor that in humans is encoded by the ESRRG gene. This gene encodes a member of the estrogen receptor-related receptor (ESRR) family, which belongs to the nuclear hormone receptor superfamily. All members of the ESRR family share an almost identical DNA binding domain, which is composed of two C4-type zinc finger motifs. The ESRR members are orphan nuclear receptors, they bind to the estrogen response element and steroidogenic factor 1 response element, and activate genes controlled by both response elements in the absence of any ligands. The ESRR family is closely related to the estrogen receptor (ER) family. They share target genes, co-regulators and promoters, and by targeting the same set of genes, the ESRRs seem to interfere with the ER-mediated estrogen response in various ways. It has been reported that the family member encoded by this gene functions as a transcriptional activator of DNA cytosine-5-methyltransferases 1 (Dnmt1) expression by binding to its response elements in the DNMT1 promoters, modulates cell proliferation and estrogen signaling in breast cancer, and negatively regulates bone morphogenetic protein 2-induced osteoblast differentiation and bone formation. Multiple alternatively spliced transcript variants have been identified, which mainly differ at the 5' end and some of which encode protein isoforms differing in the N-terminal region.
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分子量
- 51 kDa
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基因ID
- 2104
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UniProt
- P62508
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途径
- Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway
抗原
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