PDGFRB 抗体 (AA 911-992)
(2 references)Quick Overview for PDGFRB 抗体 (AA 911-992) (ABIN5693171)
抗原
See all PDGFRB 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 911-992
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原理
- Anti-PDGF Receptor beta/PDGFRB Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-PDGF Receptor beta/PDGFRB Antibody Picoband® (ABIN5693171). Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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免疫原
- E. coli-derived human PDGFRB recombinant protein (Position: E911-L992).
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亚型
- IgG
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anti-Platelet Derived Growth Factor Receptor beta (PDGFRB) (AA 33-133) antibody
PDGFRB 适用: 人 WB, ELISA, IP, PLA 宿主: 小鼠 Monoclonal 4C12 unconjugated
anti-Platelet Derived Growth Factor Receptor beta (PDGFRB) (AA 887-1106) antibodyPDGFRB 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Platelet Derived Growth Factor Receptor beta (PDGFRB) (AA 981-1066) antibodyPDGFRB 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Platelet Derived Growth Factor Receptor beta (PDGFRB) (AA 1-1106) antibodyPDGFRB 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-Platelet Derived Growth Factor Receptor beta (PDGFRB) (AA 40-72) antibodyPDGFRB 适用: 人 WB, ELISA, IHC, IF, FACS 宿主: 兔 Polyclonal unconjugated
anti-Platelet Derived Growth Factor Receptor beta (PDGFRB) (AA 33-133) antibodyPDGFRB 适用: 人, 小鼠 ELISA, FACS 宿主: 小鼠 Monoclonal 2G7B7 unconjugated
anti-Platelet Derived Growth Factor Receptor beta (PDGFRB) antibodyPDGFRB 适用: 人 WB, IF 宿主: 小鼠 Monoclonal 1G9 unconjugated
anti-Platelet Derived Growth Factor Receptor beta (PDGFRB) (AA 1-1106) antibodyPDGFRB 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Platelet Derived Growth Factor Receptor beta (PDGFRB) antibodyMicroarray verified PDGFRB 适用: 人, 小鼠 IHC 宿主: 小鼠 Monoclonal MAB472367 unconjugated
anti-Platelet Derived Growth Factor Receptor beta (PDGFRB) (AA 718-767) antibodyPDGFRB 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL
ELISA, 0.1-0.5 μg/mL
1. Lindahl P, Hellström M, Kalén M, Karlsson L, Pekny M, Pekna M, Soriano P, Betsholtz C (1998). "Paracrine PDGF-B/PDGF-Rbeta signaling controls mesangial cell development in kidney glomeruli". Development. 125 (17): 3313-22. 2. Soriano P (1994). "Abnormal kidney development and hematological disorders in PDGF beta-receptor mutant mice". Genes & Development. 8 (16): 1888-96. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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: "Preventative effect of Astragalus flavescens on hepatic fibrosis in rats and its mechanism of action." in: Experimental and therapeutic medicine, Vol. 6, Issue 4, pp. 904-908, (2013) (PubMed).
: "RNA interference targeting the platelet-derived growth factor receptor beta subunit ameliorates experimental hepatic fibrosis in rats." in: Liver international : official journal of the International Association for the Study of the Liver, Vol. 28, Issue 10, pp. 1446-57, (2009) (PubMed).
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: "Preventative effect of Astragalus flavescens on hepatic fibrosis in rats and its mechanism of action." in: Experimental and therapeutic medicine, Vol. 6, Issue 4, pp. 904-908, (2013) (PubMed).
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- PDGFRB (Platelet Derived Growth Factor Receptor beta (PDGFRB))
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别名
- PDGFRB
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背景
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Synonyms: Platelet-derived growth factor receptor beta, PDGF-R-beta, PDGFR-beta, Beta platelet-derived growth factor receptor, Beta-type platelet-derived growth factor receptor, CD140 antigen-like family member B, Platelet-derived growth factor receptor 1, PDGFR-1, CD140b, PDGFRB, PDGFR, PDGFR1
Background: Beta-type platelet-derived growth factor receptor is a protein that in humans is encoded by the PDGFRB gene. The protein encoded by this gene is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer (PDGFB or PDGFD) or a heterodimer (PDGFA and PDGFB). This gene is essential for normal development of the cardiovascular system and aids in rearrangement of the actin cytoskeleton. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor, all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the ETV6 gene, results in chronic myeloproliferative disorder with eosinophilia.
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分子量
- 120 kDa
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基因ID
- 5159
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UniProt
- P09619
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途径
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Inositol Metabolic Process, Glycosaminoglycan Metabolic Process, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling
抗原
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