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- 抗原 See all ASXL1 抗体
- ASXL1 (Additional Sex Combs Like 1 (ASXL1))
- 适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ASXL1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 品牌
- Picoband™
- 序列
- KKERTWAEAA RLVLENYSDA PMTPKQILQV IEAE
- 交叉反应 （详细）
- No cross reactivity with other proteins.
- 产品特性
- Rabbit IgG polyclonal antibody for ASXL1 detection. Tested with WB in Human,Mouse,Rat.
- 免疫原
- A synthetic peptide corresponding to a sequence of human ASXL1 (KKERTWAEAARLVLENYSDAPMTPKQILQVIEAE).
- Top Product
- Discover our top product ASXL1 Primary Antibody
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anti-Additional Sex Combs Like 1 (ASXL1) (AA 1-84) antibody
ASXL1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 6E2 unconjugated
anti-Additional Sex Combs Like 1 (ASXL1) (AA 521-549) antibodyASXL1 适用: 小鼠 WB, FACS, IF, IHC (p) 宿主: 兔 Polyclonal RB24070 unconjugated
anti-Additional Sex Combs Like 1 (ASXL1) (AA 521-549) antibodyASXL1 适用: 人, 小鼠 WB, FACS, IF, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Additional Sex Combs Like 1 (ASXL1) antibodyASXL1 适用: 人 DB 宿主: 小鼠 Monoclonal 2049C2a unconjugated
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- 应用备注
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Recommended Detection Systems: Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.
Application Details: Western blot, 0.1-0.5 μg/mL
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
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- 抗原
- ASXL1 (Additional Sex Combs Like 1 (ASXL1))
- 别名
- ASXL1 (ASXL1 产品)
- 背景
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Synonyms: Putative Polycomb group protein ASXL1, Additional sex combs-like protein 1, ASXL1, KIAA0978
Tissue Specificity: Widely expressed at low level. Expressed in heart, brain, skeletal muscle, placenta, pancreas, spleen, prostate, small intestine, colon, peripheral blood, leukocytes, bone marrow and fetal liver. Highly expressed in testes.
Background: Putative Polycomb group protein ASXL1 is a protein that in humans is encoded by the ASXL1 gene. This gene is similar to the Drosophila additional sex combs gene, which encodes a chromatin-binding protein required for normal determination of segment identity in the developing embryo. The protein is a member of the Polycomb group of proteins, which are necessary for the maintenance of stable repression of homeotic and other loci. The protein is thought to disrupt chromatin in localized areas, enhancing transcription of certain genes while repressing the transcription of other genes. The protein encoded by this gene functions as a ligand-dependent co-activator for retinoic acid receptor in cooperation with nuclear receptor coactivator 1. Mutations in this gene are associated with myelodysplastic syndromes and chronic myelomonocytic leukemia. Alternative splicing results in multiple transcript variants.
- 途径
- Retinoic Acid Receptor Signaling Pathway
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