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AGRP 抗体 (AA 82-131)

This anti-AGRP antibody is a 兔 多克隆 antibody detecting AGRP in IHC 和 ELISA. Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN5693160
发货至: 中国

Quick Overview for AGRP 抗体 (AA 82-131) (ABIN5693160)

抗原

See all AGRP 抗体
AGRP (Agouti Related Protein Homolog (Mouse) (AGRP))

适用

人, 大鼠, 小鼠

宿主

  • 41
  • 5
  • 3
  • 2

克隆类型

  • 44
  • 7
多克隆

标记

  • 30
  • 11
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This AGRP antibody is un-conjugated

应用范围

  • 34
  • 22
  • 19
  • 13
  • 9
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Immunohistochemistry (IHC), ELISA
  • 抗原表位

    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    AA 82-131

    原理

    Anti-AGRP Antibody

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-AGRP Antibody Picoband® (ABIN5693160). Tested in ELISA, IHC applications. This antibody reacts with Human, Mouse, Rat.

    免疫原

    E. coli-derived mouse AGRP recombinant protein (Position: S82-T131).

    亚型

    IgG
  • 应用备注

    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL
    ELISA, 0.1-0.5 μg/mL
    1. Ollmann MM, Wilson BD, Yang YK, Kerns JA, Chen Y, Gantz I, Barsh GS (Oct 1997). "Antagonism of central melanocortin receptors in vitro and in vivo by agouti-related protein". Science. 278 (5335): 135-8. 2. Shutter JR, Graham M, Kinsey AC, Scully S, Lüthy R, Stark KL (Mar 1997). "Hypothalamic expression of ART, a novel gene related to agouti, is up-regulated in obese and diabetic mutant mice". Genes & Development.11 (5): 593-602.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    AGRP (Agouti Related Protein Homolog (Mouse) (AGRP))

    别名

    Agrp

    背景

    Synonyms: Agouti-related protein, Agrp, Agrt, Art

    Tissue Specificity: Expressed in arcuate nucleus and median eminence, adrenal gland (medulla), hypothalamus, testis, and lung.

    Background: Agouti-related protein (AgRP), also called agouti-related peptide, is a neuropeptide produced in the brain by the AgRP/NPY neuron. In humans, the agouti-related peptide is encoded by the AGRP gene. This gene encodes an antagonist of the melanocortin-3 and melanocortin-4 receptor. It appears to regulate hypothalamic control of feeding behavior via melanocortin receptor and/or intracellular calcium regulation, and thus plays a role in weight homeostasis. Mutations in this gene have been associated with late on-set obesity.

    分子量

    49 kDa

    基因ID

    11604

    UniProt

    P56473

    途径

    Feeding Behaviour, Photoperiodism
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