AGRP 抗体 (AA 82-131)
Quick Overview for AGRP 抗体 (AA 82-131) (ABIN5693160)
抗原
See all AGRP 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 82-131
-
原理
- Anti-AGRP Antibody
-
交叉反应 （详细）
- No cross-reactivity with other proteins.
-
产品特性
- Anti-AGRP Antibody Picoband® (ABIN5693160). Tested in ELISA, IHC applications. This antibody reacts with Human, Mouse, Rat.
-
免疫原
- E. coli-derived mouse AGRP recombinant protein (Position: S82-T131).
-
亚型
- IgG
-
-
anti-Agouti Related Protein Homolog (Mouse) (AGRP) (AA 21-131) antibody
AGRP 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Agouti Related Protein Homolog (Mouse) (AGRP) (AA 20-130) antibodyAGRP 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Agouti Related Protein Homolog (Mouse) (AGRP) (AA 83-132) antibodyAGRP 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Agouti Related Protein Homolog (Mouse) (AGRP) (AA 21-132) antibodyAGRP 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Agouti Related Protein Homolog (Mouse) (AGRP) (AA 34-127) antibodyAGRP 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Agouti Related Protein Homolog (Mouse) (AGRP) (C-Term) antibodyVerified AGRP 适用: 人 IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
-
-
应用备注
-
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL
ELISA, 0.1-0.5 μg/mL
1. Ollmann MM, Wilson BD, Yang YK, Kerns JA, Chen Y, Gantz I, Barsh GS (Oct 1997). "Antagonism of central melanocortin receptors in vitro and in vivo by agouti-related protein". Science. 278 (5335): 135-8. 2. Shutter JR, Graham M, Kinsey AC, Scully S, Lüthy R, Stark KL (Mar 1997). "Hypothalamic expression of ART, a novel gene related to agouti, is up-regulated in obese and diabetic mutant mice". Genes & Development.11 (5): 593-602. -
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
-
-
- AGRP (Agouti Related Protein Homolog (Mouse) (AGRP))
-
别名
- Agrp
-
背景
-
Synonyms: Agouti-related protein, Agrp, Agrt, Art
Tissue Specificity: Expressed in arcuate nucleus and median eminence, adrenal gland (medulla), hypothalamus, testis, and lung.
Background: Agouti-related protein (AgRP), also called agouti-related peptide, is a neuropeptide produced in the brain by the AgRP/NPY neuron. In humans, the agouti-related peptide is encoded by the AGRP gene. This gene encodes an antagonist of the melanocortin-3 and melanocortin-4 receptor. It appears to regulate hypothalamic control of feeding behavior via melanocortin receptor and/or intracellular calcium regulation, and thus plays a role in weight homeostasis. Mutations in this gene have been associated with late on-set obesity.
-
分子量
- 49 kDa
-
基因ID
- 11604
-
UniProt
- P56473
-
途径
- Feeding Behaviour, Photoperiodism
抗原
-
